Deontological and altruistic guilt: evidence for distinct neurobiological substrates.

Détails

ID Serval
serval:BIB_EEAA76C54F52
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Deontological and altruistic guilt: evidence for distinct neurobiological substrates.
Périodique
Human Brain Mapping
Auteur(s)
Basile B., Mancini F., Macaluso E., Caltagirone C., Frackowiak R.S., Bozzali M.
ISSN
1097-0193[electronic], 1065-9471[linking]
Statut éditorial
Publié
Date de publication
2011
Volume
32
Numéro
2
Pages
229-239
Langue
anglais
Résumé
The feeling of guilt is a complex mental state underlying several human behaviors in both private and social life. From a psychological and evolutionary viewpoint, guilt is an emotional and cognitive function, characterized by prosocial sentiments, entailing specific moral believes, which can be predominantly driven by inner values (deontological guilt) or by more interpersonal situations (altruistic guilt). The aim of this study was to investigate whether there is a distinct neurobiological substrate for these two expressions of guilt in healthy individuals. We first run two behavioral studies, recruiting a sample of 72 healthy volunteers, to validate a set of stimuli selectively evoking deontological and altruistic guilt, or basic control emotions (i.e., anger and sadness). Similar stimuli were reproduced in a event-related functional magnetic resonance imaging (fMRI) paradigm, to investigate the neural correlates of the same emotions, in a new sample of 22 healthy volunteers. We show that guilty emotions, compared to anger and sadness, activate specific brain areas (i.e., cingulate gyrus and medial frontal cortex) and that different neuronal networks are involved in each specific kind of guilt, with the insula selectively responding to deontological guilt stimuli. This study provides evidence for the existence of distinct neural circuits involved in different guilty feelings. This complex emotion might account for normal individual attitudes and deviant social behaviors. Moreover, an abnormal processing of specific guilt feelings might account for some psychopathological manifestation, such as obsessive-compulsive disorder and depression.
Pubmed
Web of science
Création de la notice
08/03/2011 9:59
Dernière modification de la notice
03/03/2018 22:33
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