T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension.

Détails

Ressource 1Télécharger: BIB_EE8EDC0ACBE8.P001.pdf (2083.25 [Ko])
Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_EE8EDC0ACBE8
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension.
Périodique
Nucleic Acids Research
Auteur(s)
Di Tommaso P., Moretti S., Xenarios I., Orobitg M., Montanyola A., Chang J.M., Taly J.F., Notredame C.
ISSN
1362-4962 (Electronic)
ISSN-L
0305-1048
Statut éditorial
Publié
Date de publication
2011
Volume
39
Numéro
Web Server issue
Pages
W13-W17
Langue
anglais
Résumé
This article introduces a new interface for T-Coffee, a consistency-based multiple sequence alignment program. This interface provides an easy and intuitive access to the most popular functionality of the package. These include the default T-Coffee mode for protein and nucleic acid sequences, the M-Coffee mode that allows combining the output of any other aligners, and template-based modes of T-Coffee that deliver high accuracy alignments while using structural or homology derived templates. These three available template modes are Expresso for the alignment of protein with a known 3D-Structure, R-Coffee to align RNA sequences with conserved secondary structures and PSI-Coffee to accurately align distantly related sequences using homology extension. The new server benefits from recent improvements of the T-Coffee algorithm and can align up to 150 sequences as long as 10,000 residues and is available from both http://www.tcoffee.org and its main mirror http://tcoffee.crg.cat.
Pubmed
Open Access
Oui
Création de la notice
05/10/2011 10:27
Dernière modification de la notice
20/08/2019 16:16
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