Darstellung von transsynaptischer retrograder Degeneration bei homonymem RGCL-Verlust mittels OCT Transsynaptic Retrograde Degeneration: Clinical Evidence with Homonymous RGCL Loss on OCT.

Détails

ID Serval
serval:BIB_EE435A2B313C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Darstellung von transsynaptischer retrograder Degeneration bei homonymem RGCL-Verlust mittels OCT Transsynaptic Retrograde Degeneration: Clinical Evidence with Homonymous RGCL Loss on OCT.
Périodique
Klinische Monatsblatter Fur Augenheilkunde
Auteur(s)
Meier P., Maeder P., Borruat F.X.
ISSN
1439-3999 (Electronic)
ISSN-L
0023-2165
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
233
Numéro
4
Pages
396-398
Langue
anglais
Résumé
Background: Retinal thinning after a retrogeniculate lesion (transsynaptic retrograde degeneration) was first described 50 years ago, but has long been a controversial issue. It is now possible to use OCT for the in vivo measurement of retinal thickness. Material and Methods: This was a retrospective study of patients with homonymous visual field loss, with SD-OCT assessment (RNFL and RGCL measurements) in isolated retrogeniculate lesions, subsequently confirmed by a neuroradiologist. Results: Nine patients with vascular, inflammatory or tumour brain lesions were included in the study. Homonymous RGCL thinning was found in all patients, and correlated with the visual field defect. No correlation was found with RNFL. Conclusions: The homonymous defect of RGCL in patients with retrogeniculate lesions demonstrates the presence of transsynaptic retrograde degeneration. RGCL is a better predictor of visual field defects than RNFL measurement.
Pubmed
Web of science
Création de la notice
10/05/2016 17:34
Dernière modification de la notice
20/08/2019 16:15
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