Association of socioeconomic status with inflammatory markers: a two cohort comparison.

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State: Public
Version: Author's accepted manuscript
Serval ID
serval:BIB_ED8545161FA1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Association of socioeconomic status with inflammatory markers: a two cohort comparison.
Journal
Preventive Medicine
Author(s)
Fraga S., Marques-Vidal P., Vollenweider P., Waeber G., Guessous I., Paccaud F., Barros H., Stringhini S.
ISSN
1096-0260 (Electronic)
ISSN-L
0091-7435
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
71
Pages
12-19
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish
Abstract
OBJECTIVE: To assess the association between socioeconomic status (SES) and inflammatory markers using two different European population samples.
METHODS: We used data from the CoLaus (N=6412, Lausanne, Switzerland) and EPIPorto (N=1205, Porto, Portugal) studies. Education and occupational position were used as indicators of socioeconomic status (SES). High-sensitivity C-reactive protein (hs-CRP) was available for both cohorts. Interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) were available in CoLaus; leukocyte count and fibrinogen in EPIPorto.
RESULTS: We showed that low SES was significantly associated with high inflammation in both studies. We also showed that behavioural factors contributed the most to SES differences in inflammation. In both studies the larger difference between the lowest and the highest SES was observed for hs-CRP. In the Swiss sample, a linear association between education and hs-CRP persisted after adjustment for all mediating factors and confounders considered (p for linear trend <0.001).
CONCLUSION: Large social differences exist in inflammatory activity, in part independently from demographic and behavioural factors, chronic conditions and medication use. SES differences in inflammation are also similar in countries with different underlying socioeconomic conditions.
Pubmed
Web of science
Open Access
Yes
Create date
15/01/2015 16:02
Last modification date
20/08/2019 16:15
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