E-liquid flavors and nicotine concentration choices over 6 months after a smoking cessation attempt with ENDS: Secondary analyses of a randomized controlled trial.

Details

Serval ID
serval:BIB_ED36163CF44B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
E-liquid flavors and nicotine concentration choices over 6 months after a smoking cessation attempt with ENDS: Secondary analyses of a randomized controlled trial.
Journal
Tobacco prevention & cessation
Author(s)
Mosimann A.F., Güttinger E.M., Tal K., Schoeni A., Baggio S., Sambiagio N., Berthet A., Jacot-Sadowski I., Humair J.P., Brutsche M., Frei A., Haller M.L., Auer R., Jakob J.
ISSN
2459-3087 (Electronic)
ISSN-L
2459-3087
Publication state
Published
Issued date
2025
Peer-reviewed
Oui
Volume
11
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Many tobacco smokers try to quit with electronic nicotine delivery systems (ENDS or e-cigarettes). We aimed to describe e-liquid flavors and nicotine concentration use over 6 months in a prospective cohort of smokers willing to quit with ENDS.
We included 622 participants from the intervention group of the Efficacy, Safety and Toxicology of ENDS randomized controlled trial. Participants were adult smokers smoking at least five cigarettes a day. They received free ENDS and a choice of 6 e-liquid flavors in 4 nicotine concentrations and smoking cessation counseling. We tracked flavor choice and nicotine concentration at 1, 2, 4, and 8 weeks, and at 6 months, after the target quit date, comparing participants who reported only vaping (exclusive e-cigarette users) to those who vaped and smoked (dual users) over the last 7 days. We applied multivariable regression models to compute adjusted risk ratios (ARR).
At Week 1, 66% (n=409) were exclusive e-cigarette users, and 21% (n=129) were dual users. At Month 6, 43% (n=266) were exclusive e-cigarette users, and 16% (n=102) were dual users. While flavor choices were similar at Week 1, at 6 months, exclusive e-cigarette users reported using more fruity flavors than dual users (31% vs 22%, ARR=2.10; 95% CI: 1.21-3.66). The nicotine concentration used initially was similar in both groups and diminished over time. At 6 months, exclusive e-cigarette users used a lower mean nicotine concentration than dual users (6.3 vs 8.2 mg/mL, difference= -1.55; 95% CI: -2.84 - -0.25 mg/mL).
After 6 months, exclusive e-cigarette users used more fruity-flavored e-liquids and chose a lower mean nicotine concentration than dual users.
Keywords
ENDS, e-cigarette, e-liquid, flavor, nicotine concentration, smoking cessation
Pubmed
Web of science
Open Access
Yes
Create date
20/01/2025 10:03
Last modification date
04/02/2025 7:25
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