Export of salicylic acid from the chloroplast requires the multidrug and toxin extrusion-like transporter EDS5.

Détails

ID Serval
serval:BIB_EBE56335EA4C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Export of salicylic acid from the chloroplast requires the multidrug and toxin extrusion-like transporter EDS5.
Périodique
Plant Physiology
Auteur(s)
Serrano M., Wang B., Aryal B., Garcion C., Abou-Mansour E., Heck S., Geisler M., Mauch F., Nawrath C., Métraux J.P.
ISSN
1532-2548 (Electronic)
ISSN-L
0032-0889
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
162
Numéro
4
Pages
1815-1821
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
Salicylic acid (SA) is central for the defense of plants to pathogens and abiotic stress. SA is synthesized in chloroplasts from chorismic acid by an isochorismate synthase (ICS1); SA biosynthesis is negatively regulated by autoinhibitory feedback at ICS1. Genetic studies indicated that the multidrug and toxin extrusion transporter ENHANCED DISEASE SUSCEPTIBILITY5 (EDS5) of Arabidopsis (Arabidopsis thaliana) is necessary for SA accumulation after biotic and abiotic stress, but so far it is not understood how EDS5 controls the biosynthesis of SA. Here, we show that EDS5 colocalizes with a marker of the chloroplast envelope and that EDS5 functions as a multidrug and toxin extrusion-like transporter in the export of SA from the chloroplast to the cytoplasm in Arabidopsis, where it controls the innate immune response. The location at the chloroplast envelope supports a model of the effect of EDS5 on SA biosynthesis: in the eds5 mutant, stress-induced SA is trapped in the chloroplast and inhibits its own accumulation by autoinhibitory feedback.
Mots-clé
Arabidopsis/drug effects, Arabidopsis/physiology, Arabidopsis Proteins/genetics, Arabidopsis Proteins/metabolism, Biological Transport, Carbonyl Cyanide m-Chlorophenyl Hydrazone/pharmacology, Chloroplasts/genetics, Chloroplasts/metabolism, Cytoplasm/genetics, Cytoplasm/metabolism, Immunity, Innate, Membrane Transport Proteins/genetics, Membrane Transport Proteins/metabolism, Molecular Sequence Data, Mutation, Nigericin/pharmacology, Plants, Genetically Modified, Protoplasts/metabolism, Salicylic Acid/metabolism, Ultraviolet Rays
Pubmed
Web of science
Open Access
Oui
Création de la notice
06/10/2016 14:00
Dernière modification de la notice
20/08/2019 16:14
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