Long-term results of deep sclerectomy with collagen implant.

Details

Serval ID
serval:BIB_EB7FB0A943CD
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Long-term results of deep sclerectomy with collagen implant.
Journal
Journal of Cataract and Refractive Surgery
Author(s)
Shaarawy T., Mansouri K., Schnyder C., Ravinet E., Achache F., Mermoud A.
ISSN
0886-3350
Publication state
Published
Issued date
2004
Peer-reviewed
Oui
Volume
30
Number
6
Pages
1225-1231
Language
english
Abstract
PURPOSE: To study prospectively the success rate and complications of deep sclerectomy with collagen implant (DSCI). SETTING: Glaucoma Unit, Department of Ophthalmology, Hôpital Ophtalmique Jules Gonin, University of Lausanne, Lausanne, Switzerland. METHODS: This nonrandomized prospective trial comprised 105 eyes of 105 patients with medically uncontrolled primary and secondary open-angle glaucoma. Visual acuity, intraocular pressure (IOP), and slitlamp examinations were performed before surgery and after surgery at 1 and 7 days, and 1, 3, 6, 9, 12, 18, 24, 30, 36, 48, 54, 60, 66, 72, 78, 84, 90, and 96 months. Visual field examinations were repeated every 6 months. RESULTS: Mean follow-up period was 64 months +/- 26.6 (SD). Mean preoperative IOP was 26.8 +/- 7.7 mm Hg, and mean postoperative IOP was 5.2 +/- 3.35 mm Hg at day 1 and 12 +/- 3 mm Hg at month 78. At 96 months, the qualified success rate (ie, patients who achieved IOP <21 mm Hg with and without medication) was 91%, and the complete success rate (ie, IOP <21 mm Hg without medication) was 57%. At 96 months, 34% of patients had an IOP <21 mm Hg with medication. Fifty-one patients (49%) achieved an IOP < or =15 mm Hg without medication. Neodymium:YAG goniopuncture was performed in 54 patients (51%); mean time of goniopuncture performance was 21 months, and mean IOP before goniopuncture was 20 mm Hg, dropping to 11 mm Hg after goniopuncture. No shallow or flat anterior chamber, endophthalmitis, or surgery-induced cataract was observed. However, 26 patients (25%) showed a progression of preexisting senile cataract (mean time 26 months; range 18 to 37 months). Injections of 5-fluorouracil were administered to 25 patients (23%) who underwent DSCI to salvage encysted blebs. Mean number of medications per patient was reduced from 2.3 +/- 0.7 to 0.5 +/- 0.7 (signed rank P<.0001). CONCLUSION: Deep sclerectomy with collagen implant appears to provide stable and reasonable control of IOP at long-term follow-up with few immediate postoperative complications.
Keywords
Aged, Collagen, Female, Follow-Up Studies, Glaucoma Drainage Implants, Glaucoma, Open-Angle, Humans, Intraocular Pressure, Male, Prognosis, Prospective Studies, Sclera, Sclerostomy, Visual Acuity, Visual Fields
Pubmed
Web of science
Create date
28/02/2008 13:01
Last modification date
20/08/2019 16:13
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