A narrative review of the intermediate category of the antimicrobial susceptibility test: relation with dosing and possible impact on antimicrobial stewardship.
Details
Serval ID
serval:BIB_EA57B66CFE2B
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
A narrative review of the intermediate category of the antimicrobial susceptibility test: relation with dosing and possible impact on antimicrobial stewardship.
Journal
The Journal of antimicrobial chemotherapy
ISSN
1460-2091 (Electronic)
ISSN-L
0305-7453
Publication state
Published
Issued date
01/02/2023
Peer-reviewed
Oui
Volume
78
Number
2
Pages
338-345
Language
english
Notes
Publication types: Review ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
The interpretation of 'susceptible (S)' or 'resistant (R)' results of antimicrobial susceptibility testing is easily understood, but the interpretation of the 'intermediate (I)' category can be confusing. This review critically discusses how this categorization (clinical breakpoints) comes into being with the emphasis on the use of pharmacokinetics and pharmacodynamic data. It discusses the differences between the 'I' according to the CLSI and the EUCAST. This review also discusses the recent EUCAST change of the 'I' definition, and the impact of this change from laboratory and clinical points of view.
Keywords
Anti-Bacterial Agents/therapeutic use, Anti-Bacterial Agents/pharmacokinetics, Antimicrobial Stewardship, Microbial Sensitivity Tests, Laboratories
Pubmed
Web of science
Create date
03/01/2023 6:47
Last modification date
08/03/2023 7:46
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