Rhea-a manually curated resource of biochemical reactions.

Détails

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Etat: Public
Version: Final published version
ID Serval
serval:BIB_E9A04015506E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Rhea-a manually curated resource of biochemical reactions.
Périodique
Nucleic Acids Research
Auteur(s)
Alcántara R., Axelsen K.B., Morgat A., Belda E., Coudert E., Bridge A., Cao H., de Matos P., Ennis M., Turner S., Owen G., Bougueleret L., Xenarios I., Steinbeck C.
ISSN
1362-4962 (Electronic)
ISSN-L
0305-1048
Statut éditorial
Publié
Date de publication
2012
Volume
40
Numéro
Database issue
Pages
D754-D760
Langue
anglais
Résumé
Rhea (http://www.ebi.ac.uk/rhea) is a comprehensive resource of expert-curated biochemical reactions. Rhea provides a non-redundant set of chemical transformations for use in a broad spectrum of applications, including metabolic network reconstruction and pathway inference. Rhea includes enzyme-catalyzed reactions (covering the IUBMB Enzyme Nomenclature list), transport reactions and spontaneously occurring reactions. Rhea reactions are described using chemical species from the Chemical Entities of Biological Interest ontology (ChEBI) and are stoichiometrically balanced for mass and charge. They are extensively manually curated with links to source literature and other public resources on metabolism including enzyme and pathway databases. This cross-referencing facilitates the mapping and reconciliation of common reactions and compounds between distinct resources, which is a common first step in the reconstruction of genome scale metabolic networks and models.
Mots-clé
Biochemical Processes, Databases, Factual, Enzymes/metabolism, Internet, Metabolic Networks and Pathways, Software
Pubmed
Web of science
Open Access
Oui
Création de la notice
17/10/2012 10:30
Dernière modification de la notice
20/08/2019 16:12
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