Evolution of right ventricular size over time after tetralogy of Fallot repair: a longitudinal cardiac magnetic resonance study.

Détails

ID Serval
serval:BIB_E97657512C87
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Evolution of right ventricular size over time after tetralogy of Fallot repair: a longitudinal cardiac magnetic resonance study.
Périodique
European heart journal cardiovascular Imaging
Auteur(s)
Rutz T., Ghandour F., Meierhofer C., Naumann S., Martinoff S., Lange R., Ewert P., Stern H.C., Fratz S.
ISSN
2047-2412 (Electronic)
ISSN-L
2047-2404
Statut éditorial
Publié
Date de publication
01/03/2017
Peer-reviewed
Oui
Volume
18
Numéro
3
Pages
364-370
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
It is commonly believed that pulmonary regurgitation (PR) after surgical repair of tetralogy of Fallot (TOF) leads to progressive right ventricular (RV) enlargement. However, progressive RV dilatation has never clearly been documented in this patient population. Therefore, we studied the size of the RV over time in patients after surgical TOF repair.
Fifty-one consecutive patients after surgical TOF repair underwent at least two cardiovascular magnetic resonance (CMR) exams using a single CMR scanner. Patients with RV outflow tract obstruction, interventions other than the initial repair and CMR exams with use of sedation were excluded. Three subgroups with different repair techniques were studied: transannular patch repair [n = 22, age 17 ± 10 years], subvalvular patch repair [n = 15, age 22 ± 8 years], or non-patch repair/infundibulectomy (n = 14, age 28 ± 11 years). Right ventricular end-diastolic volume index (RVEDVI) and PR fraction did not change during the 37 ± 21 months follow-up between first and last CMR in the whole group (RVEDVI: 118 ± 23 mL/m2 vs. 119 ± 23 mL/m2, P = 0.720; PR fraction: 33% (23-40%) vs. 32% (24-39%), P = 0.268). RVEDVI remained stable in all subgroups (transannular patch: 120 ± 21 mL/m2 vs. 122 ± 22 mL/m2, subvalvular patch: 112 ± 23 mL/m2 vs. 111 ± 23 mL/m2, non-patch: 123 ± 28 mL/m2 vs. 123 ± 23 mL/m2, P = 0.827). RVEDVI at last CMR did not differ between groups (P = 0.301).
This study shows no progression of RV dilatation in patients after surgical repair of TOF with moderately dilated RVs and significant PR during a 3-year follow-up. RV dilatation in our patient group seems to be independent from surgical repair techniques.

Mots-clé
Adolescent, Adult, Age Factors, Analysis of Variance, Cardiac Surgical Procedures/methods, Chi-Square Distribution, Child, Cohort Studies, Female, Follow-Up Studies, Humans, Longitudinal Studies, Magnetic Resonance Imaging, Cine/methods, Male, Middle Aged, Risk Assessment, Statistics, Nonparametric, Tetralogy of Fallot/diagnostic imaging, Tetralogy of Fallot/surgery, Time Factors, Ventricular Function, Right/physiology, Ventricular Remodeling/physiology, Young Adult, RV dilatation, cardiac magnetic resonance, congenital heart disease, tetralogy of Fallot, transannular patch
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/04/2017 17:09
Dernière modification de la notice
20/08/2019 17:12
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