Piecemeal recruitment of left-lateralized brain areas during reading: a spatio-functional account.

Détails

ID Serval
serval:BIB_E900B6423B34
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Piecemeal recruitment of left-lateralized brain areas during reading: a spatio-functional account.
Périodique
Neuroimage
Auteur(s)
Levy J., Pernet C., Treserras S., Boulanouar K., Berry I., Aubry F., Demonet J.F., Celsis P.
ISSN
1095-9572 (Electronic)
ISSN-L
1053-8119
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Volume
43
Numéro
3
Pages
581-591
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish
Résumé
Neuroimaging studies of reading converge to suggest that linguistically elementary stimuli are confined to the activation of bilateral posterior regions, whereas linguistically complex stimuli additionally recruit left hemispheric anterior regions, raising the hypotheses of a gradual bilateral-to-left and a posterior-to-anterior recruitment of reading related areas. Here, we tested these two hypotheses by contrasting a repertoire of eight categories of stimuli ranging from simple orthographic-like characters to words and pseudowords in a single experiment, and by measuring BOLD signal changes and connectivity while 16 fluent readers passively viewed the stimuli. Our results confirm the existence of a bilateral-to-left and posterior-to-anterior recruitment of reading related areas, straightforwardly resulting from the increase in stimuli's linguistic processing load, which reflects reading processes: visual analysis, orthographic encoding and phonological decoding. Connectivity analyses strengthened the validity of these observations and additionally revealed an enhancement of the left parieto-frontal information trafficking for higher linguistic processing. Our findings clearly establish the notion of a gradual spatio-functional recruitment of reading areas and demonstrate, to the best of our knowledge, the first evidence of a robust and staged link between the level of linguistic processing, the spatial distribution of brain activity and its information trafficking.
Mots-clé
Adult, Brain/physiology, Brain Mapping, Female, Functional Laterality/physiology, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Pattern Recognition, Visual/physiology, Reading
Pubmed
Web of science
Création de la notice
24/03/2013 20:05
Dernière modification de la notice
03/03/2018 22:22
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