Temperament and self-esteem in high-risk offspring of bipolar parents: Vulnerability and scar effects.

Détails

ID Serval
serval:BIB_E8D88F75C474
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Temperament and self-esteem in high-risk offspring of bipolar parents: Vulnerability and scar effects.
Périodique
Journal of affective disorders
Auteur(s)
Goodday S.M., Preisig M., Gholamrezaee M., Grof P., Duffy A.
ISSN
1573-2517 (Electronic)
ISSN-L
0165-0327
Statut éditorial
Publié
Date de publication
15/01/2019
Peer-reviewed
Oui
Volume
243
Pages
209-215
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
The nature of the temporal relationship between psychological factors and mood episodes is unclear. The objectives of this study were to determine if temperament and self-esteem predict the onset of mood episodes, and if prior mood episodes influence the stability of these factors over time in high-risk offspring of bipolar parents.
Offspring of a parent with bipolar disorder participating in the Flourish Prospective Offspring Study were clinically assessed repeatedly using semi-structured KSADS-PL/SADS-L format interviews, and completed repeated measures of self-esteem, and temperament. Shared frailty survival models and mixed effects regression models were used to determine if psychological factors predicted incident mood episodes, and whether these factors change over time after the incident mood episode, respectively.
Emotionality, shyness and self-esteem were not associated with the hazard of incident major depression; however, increased activity reduced the hazard of this outcome (hazard ratio [HR]: 0.51; 95% CI: 0.27, 0.98). Emotionality and shyness scores increased, while sociability, activity and self-esteem scores decreased after the incident major depressive episode (emotionality: mean change [MC]: 0.35, p = 0.0289; shyness: MC: 0.40, p = 0.0196; sociability: MC: -0.49, p = 0.0001, activity: MC: -0.32, p = 0.0001; self-esteem: MC: -0.79, p = 0.001).
Psychological measures were based on self-report and some models had low numbers limiting the numbers of covariates included as potential confounders.
Among the assessed temperamental dimensions, activity showed a protective effect for major depressive episode onset suggesting this temperamental characteristic could serve as a protective target in high risk youth. Conversely, all assessed psychological factors shifted towards increased vulnerability after the first depressive episode.
Mots-clé
Adolescent, Bipolar Disorder/psychology, Canada/epidemiology, Child of Impaired Parents/psychology, Depressive Disorder, Major/epidemiology, Depressive Disorder, Major/psychology, Disease Susceptibility/psychology, Female, Humans, Male, Models, Statistical, Parents/psychology, Prospective Studies, Self Concept, Temperament, Young Adult, Bipolar disorder, Mood disorders, Self-esteem
Pubmed
Web of science
Création de la notice
11/10/2018 11:44
Dernière modification de la notice
20/08/2019 17:11
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