Benzodiazepine-receptor agonist prescription in a population of hospitalised patients in four psychogeriatric units in Switzerland.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_E83FF24F66AC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Benzodiazepine-receptor agonist prescription in a population of hospitalised patients in four psychogeriatric units in Switzerland.
Journal
Journal of sleep research
Author(s)
Dalmau I Ribas M., Sauser J., Gillès de Pélichy E., Méndez Rubio M., Schuster J.P., Von Gunten A., Haba-Rubio J.
ISSN
1365-2869 (Electronic)
ISSN-L
0962-1105
Publication state
Published
Issued date
02/2025
Peer-reviewed
Oui
Volume
34
Number
1
Pages
e14317
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
The aim of this study is to describe the patterns of prescription of benzodiazepine-receptor agonists in hospitalised patients in four psychogeriatric units in Switzerland. This is a retrospective cross-sectional study that included patients aged 65 years or more hospitalised in one of the four psychogeriatric units of a university hospital in Switzerland during 2019. The presence, type and dose of benzodiazepine-receptor agonists was assessed at admission and at discharge. Three-hundred and eighty-six patients (214 women, 78.2 ± 8.1 years) were included in the study; 33.4% of patients had at least one benzodiazepine-receptor agonist at admission and 22.5% at discharge. The relative reduction of benzodiazepine-receptor agonists prescription in standardised dose was 78%. Age was found to be a protective factor against benzodiazepine-receptor agonists prescription at admission (adjusted odds ratio 0.94, confidence interval 0.91-0.98), and diagnosis of substance abuse was found to be a risk factor (adjusted odds ratio 4.43, confidence interval 1.42-17.02). Longer hospital stays (> 14 days) were associated with higher reduction of benzodiazepine-receptor agonists. The prevalence of a prescription of benzodiazepine-receptor agonists at admission was high, but during the psychogeriatric hospitalisation benzodiazepine-receptor agonists prescription decreased both in absolute and relative terms.
Keywords
Humans, Switzerland, Female, Aged, Male, Cross-Sectional Studies, Retrospective Studies, Hospitalization/statistics & numerical data, Aged, 80 and over, GABA-A Receptor Agonists/therapeutic use, GABA-A Receptor Agonists/pharmacology, Benzodiazepines/therapeutic use, Length of Stay/statistics & numerical data, benzodiazepine, elderly, hospital, inpatient, insomnia symptoms, psychiatry, psychogeriatrics, sedative‐hypnotic, z‐drug
Pubmed
Web of science
Open Access
Yes
Create date
09/08/2024 9:39
Last modification date
25/02/2025 8:20
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