GLUT2-Expressing Neurons as Glucose Sensors in the Brain: Electrophysiological Analysis.

Détails

ID Serval
serval:BIB_E8138BB17B01
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
GLUT2-Expressing Neurons as Glucose Sensors in the Brain: Electrophysiological Analysis.
Périodique
Methods in molecular biology
Auteur(s)
Labouèbe G., Thorens B., Lamy C.
ISSN
1940-6029 (Electronic)
ISSN-L
1064-3745
Statut éditorial
Publié
Date de publication
2018
Peer-reviewed
Oui
Volume
1713
Pages
255-267
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Brain glucose sensing plays an essential role in the regulation of energy homeostasis. Recent publications report that neurons expressing glucose transporter GLUT2 act as glucose sensors in different regions of the brain and contribute to the control of glucose homeostasis and feeding behavior. In this chapter we describe the methods used to explore glucose sensing in genetically tagged GLUT2-expressing neurons with slice electrophysiology.
Mots-clé
Animals, Brain/physiology, Electrophysiological Phenomena, Gene Expression, Glucose/metabolism, Glucose Transporter Type 2/genetics, Glucose Transporter Type 2/metabolism, Male, Mice, Molecular Imaging, Neurons/physiology, Patch-Clamp Techniques, Electrophysiology, GLUT2, Glucose sensing, Juxtacellular, NTS, Neurons, PVT, Whole-cell
Pubmed
Création de la notice
14/12/2017 19:05
Dernière modification de la notice
20/08/2019 17:10
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