Bacillus cereus bacteraemia: comparison between haematologic and nonhaematologic patients.

Détails

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Etat: Public
Version: Final published version
ID Serval
serval:BIB_E74D69C85966
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Bacillus cereus bacteraemia: comparison between haematologic and nonhaematologic patients.
Périodique
New microbes and new infections
Auteur(s)
Tusgul S., Prod'hom G., Senn L., Meuli R., Bochud P.Y., Giulieri S.G.
ISSN-L
2052-2975
Statut éditorial
Publié
Date de publication
01/2017
Peer-reviewed
Oui
Volume
15
Pages
65-71
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish

Résumé
Bacillus cereus bacteraemia can be severe, especially among patients with haematologic malignancy. We retrospectively reviewed first episodes of true B. cereus bacteraemia (more than one positive bottle plus signs of infection) at our institution between 1997 and 2013 with the aim to compare haematologic versus nonhaematologic patients and analyse episodes with complicated outcome. Among 56 episodes of positive-blood cultures for B. cereus, 21 were considered significant. Median age was 54 years (range 23-82 years). Ten patients (48%) had a haematologic malignancy; all were neutropenic at the time of B. cereus bacteraemia. Nonhaematologic patients were either intravenous drug users (n = 3, 14%), polytraumatized (n = 3, 14%) or had multiple chronic comorbidities (n = 5, 24%). Most episodes were hospital acquired (15, 71%). Sources of bacteraemia were intravascular catheter (n = 11, 52%), digestive tract (n = 6, 29%), drug injection (n = 3, 14%) and wound (n = 1, 5%). Adequate antibiotic therapy was provided to 18 patients (86%) during a median of 17 days (range 2-253 days). The intravascular catheter was removed in eight cases (42%). Three haematologic patients had a complicated course with neurologic complications (meningoencephalitis and cerebral abscesses). Complications appeared to be associated with catheter infection (100% of complicated cases vs. 29% of noncomplicated cases). In conclusion, B. cereus bacteraemia can have a complicated course in a subset of patients, mainly those with haematologic malignancy. Catheter infection may be associated with a worse outcome with frequent neurologic complications.

Pubmed
Open Access
Oui
Création de la notice
10/01/2017 17:44
Dernière modification de la notice
20/08/2019 16:10
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