Arrhythmic episodes in patients implanted with a cardioverter-defibrillator - results from the Prospective Study on Predictive Quality with Preferencing PainFree ATP therapies (4P).

Détails

ID Serval
serval:BIB_E5BA1D17D845
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Arrhythmic episodes in patients implanted with a cardioverter-defibrillator - results from the Prospective Study on Predictive Quality with Preferencing PainFree ATP therapies (4P).
Périodique
BMC cardiovascular disorders
Auteur(s)
Regoli F., Graf D., Schaer B., Duru F., Ammann P., Stefano LMDS, Naegli B., Burri H., Zbinden R., Krasniqi N., Fromer M.
Collaborateur(s)
4P Study Group
Contributeur(s)
Moccetti T., Steffel A., Steffel J., Eriksson U.
ISSN
1471-2261 (Electronic)
ISSN-L
1471-2261
Statut éditorial
Publié
Date de publication
17/06/2019
Peer-reviewed
Oui
Volume
19
Numéro
1
Pages
146
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Résumé
Little is known about the ICD performance using enhanced detection algorithms in unselected, non-trial patients. Performance of recent generation ICD equipped with SmartShock™ technology (SST) for detection and conversion of ventricular tachyarrhythmias (VTA) was investigated.
4P was a prospective, multicenter, observational study conducted in 10 Swiss implanting centers. Patients with a Class I indication according to international guidelines were included and received an ICD with SST. ICD discrimination capability was assessed by evaluating SST performance; therapy efficacy was assessed by rate of VTA conversions by ATP and by rescue shocks.
Overall, 196 patients were included in the analysis with a mean duration of follow-up of 27.7 months (452 patient-years of observation). Patient-specific rather than recommended programming was preferred. Device-detected episodes were frequent (5147 episodes in 146 patients, 74.5%). In 44 patients (22.4%), 1274 episodes were categorized as VTA; only 215 episodes were symptomatic. ATP was the first-line therapy and highly effective (99.9% success rate at the episode level, 100.0% at the patient level). Rescue shocks were rare (66 episodes in 28 patients); 7 shocks in 5 patients (2.6%) were inappropriate. Death and hospitalization rates were low.
In a cohort of non-trial, unselected ICD patients, VTA episodes were frequent. The 4P results confirm the robustness of VTA detection by SST and the effectiveness of ATP treatment, hence limiting overall ICD shock burden.
Mots-clé
Antitachycardia pacing, Implantable cardioverter-defibrillator, Shock, Ventricular tachyarrhythmia
Pubmed
Web of science
Open Access
Oui
Création de la notice
01/08/2019 10:04
Dernière modification de la notice
21/08/2019 6:35
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