Assessing radiomics feature stability with simulated CT acquisitions.

Details

Ressource 1Download: 35304508_BIB_E3DFA740E78A.pdf (2532.93 [Ko])
State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_E3DFA740E78A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Assessing radiomics feature stability with simulated CT acquisitions.
Journal
Scientific reports
Author(s)
Flouris K., Jimenez-Del-Toro O., Aberle C., Bach M., Schaer R., Obmann M.M., Stieltjes B., Müller H., Depeursinge A., Konukoglu E.
ISSN
2045-2322 (Electronic)
ISSN-L
2045-2322
Publication state
Published
Issued date
18/03/2022
Peer-reviewed
Oui
Volume
12
Number
1
Pages
4732
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Abstract
Medical imaging quantitative features had once disputable usefulness in clinical studies. Nowadays, advancements in analysis techniques, for instance through machine learning, have enabled quantitative features to be progressively useful in diagnosis and research. Tissue characterisation is improved via the "radiomics" features, whose extraction can be automated. Despite the advances, stability of quantitative features remains an important open problem. As features can be highly sensitive to variations of acquisition details, it is not trivial to quantify stability and efficiently select stable features. In this work, we develop and validate a Computed Tomography (CT) simulator environment based on the publicly available ASTRA toolbox ( www.astra-toolbox.com ). We show that the variability, stability and discriminative power of the radiomics features extracted from the virtual phantom images generated by the simulator are similar to those observed in a tandem phantom study. Additionally, we show that the variability is matched between a multi-center phantom study and simulated results. Consequently, we demonstrate that the simulator can be utilised to assess radiomics features' stability and discriminative power.
Keywords
Machine Learning, Phantoms, Imaging, Retrospective Studies, Tomography, X-Ray Computed/methods
Pubmed
Web of science
Open Access
Yes
Create date
07/04/2022 9:53
Last modification date
23/01/2024 8:36
Usage data