Structural determinants involved in the activation and regulation of G protein-coupled receptors: lessons from the alpha1-adrenegic receptor subtypes.

Détails

ID Serval
serval:BIB_E23955380239
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Structural determinants involved in the activation and regulation of G protein-coupled receptors: lessons from the alpha1-adrenegic receptor subtypes.
Périodique
Biology of the Cell
Auteur(s)
Cotecchia S., Stanasila L., Diviani D., Björklöf K., Rossier O., Fanelli F.
ISSN
0248-4900 (Print)
ISSN-L
0248-4900
Statut éditorial
Publié
Date de publication
2004
Volume
96
Numéro
5
Pages
327-333
Langue
anglais
Résumé
The aim of a large number of studies on G protein-coupled receptors was centered on understanding the structural basis of their main functional properties. Here, we will briefly review the results obtained on the alpha1-adrenergic receptor subtypes belonging to the rhodopsin-like family of receptors. These findings contribute, on the one hand, to further understand the molecular basis of adrenergic transmission and, on the other, to provide some generalities on the structure-functional relationship of G protein-coupled receptors.
Mots-clé
Amino Acid Sequence, Animals, DNA Mutational Analysis, Humans, Models, Biological, Models, Molecular, Molecular Sequence Data, Mutation, Protein Binding, Receptors, Adrenergic, alpha-1/metabolism, Receptors, G-Protein-Coupled/chemistry, Receptors, G-Protein-Coupled/physiology, Rhodopsin/metabolism
Pubmed
Web of science
Open Access
Oui
Création de la notice
24/01/2008 11:06
Dernière modification de la notice
20/08/2019 16:06
Données d'usage