Article: article from journal or magazin.
Urease-based mucosal immunization against Helicobacter heilmannii infection induces corpus atrophy in mice
Infection and Immunity
PT - Journal Article PT - Research Support, Non-U.S. Gov't
Mucosal immunization with Helicobacter heilmannii urease B or Helicobacter pylori urease, given nasally with cholera toxin, protects BALB/c mice against H. heilmannii infection and significantly reduces a preexisting infection. However, immunization aggravates gastric corpus atrophy. Our results underline the necessity of defining immunization regimens that do not enhance mucosal damage
Animals/Atrophy/Bacterial Vaccines/immunology/Cholera Toxin/Gastric Mucosa/Pathology/Helicobacter/Helicobacter Infections/prevention & control/Immunity,Mucosal/Immunization/Mice/Mice,Inbred BALB C/Recombinant Proteins/Urease/Vaccines,Synthetic
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