Clinical spectrum of tuberculous optic neuropathy.

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Serval ID
serval:BIB_DFF4297386F2
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Clinical spectrum of tuberculous optic neuropathy.
Journal
Journal of Ophthalmic Inflammation and Infection
Author(s)
Davis E.J., Rathinam S.R., Okada A.A., Tow S.L., Petrushkin H., Graham E.M., Chee S.P., Guex-Crosier Y., Jakob E., Tugal-Tutkun I., Cunningham E.T., Leavitt J.A., Mansour A.M., Winthrop K.L., Hills W.L., Smith J.R.
ISSN
1869-5760 (Electronic)
Publication state
Published
Issued date
2012
Peer-reviewed
Oui
Volume
2
Pages
183-189
Language
english
Abstract
PURPOSE: Tuberculous optic neuropathy may follow infection with Mycobacterium tuberculosis or administration of the bacille Calmette-Guerin. However, this condition is not well described in the ophthalmic literature. METHODS: Ophthalmologists, identified through professional electronic networks or previous publications, collected standardized clinical data relating to 62 eyes of 49 patients who they had managed with tuberculous optic neuropathy. RESULTS: Tuberculous optic neuropathy was most commonly manifested as papillitis (51.6 %), neuroretinitis (14.5 %), and optic nerve tubercle (11.3 %). Uveitis was an additional ocular morbidity in 88.7 % of eyes. In 36.7 % of patients, extraocular tuberculosis was present. The majority of patients (69.4 %) had resided in and/or traveled to an endemic area. Although initial visual acuity was 20/50 or worse in 62.9 % of 62 eyes, 76.7 % of 60 eyes followed for a median of 12 months achieved visual acuities of 20/40 or better. Visual field defects were reported for 46.8 % of eyes, but these defects recovered in 63.2 % of 19 eyes with follow-up. CONCLUSION: Visual recovery from tuberculous optic neuropathy is common, if the diagnosis is recognized and appropriate treatment is instituted. A tuberculous etiology should be considered when evaluating optic neuropathy in persons from endemic areas.
Pubmed
Open Access
Yes
Create date
25/05/2012 11:01
Last modification date
20/08/2019 16:04
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