Nutrigenomics and nutrigenetics: the emerging faces of nutrition.

Details

Serval ID
serval:BIB_DE84653D432A
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Nutrigenomics and nutrigenetics: the emerging faces of nutrition.
Journal
FASEB journal
Author(s)
Mutch D.M., Wahli W., Williamson G.
ISSN
1530-6860[electronic]
Publication state
Published
Issued date
2005
Peer-reviewed
Oui
Volume
19
Number
12
Pages
1602-1616
Language
english
Abstract
The recognition that nutrients have the ability to interact and modulate molecular mechanisms underlying an organism's physiological functions has prompted a revolution in the field of nutrition. Performing population-scaled epidemiological studies in the absence of genetic knowledge may result in erroneous scientific conclusions and misinformed nutritional recommendations. To circumvent such issues and more comprehensively probe the relationship between genes and diet, the field of nutrition has begun to capitalize on both the technologies and supporting analytical software brought forth in the post-genomic era. The creation of nutrigenomics and nutrigenetics, two fields with distinct approaches to elucidate the interaction between diet and genes but with a common ultimate goal to optimize health through the personalization of diet, provide powerful approaches to unravel the complex relationship between nutritional molecules, genetic polymorphisms, and the biological system as a whole. Reluctance to embrace these new fields exists primarily due to the fear that producing overwhelming quantities of biological data within the confines of a single study will submerge the original query; however, the current review aims to position nutrigenomics and nutrigenetics as the emerging faces of nutrition that, when considered with more classical approaches, will provide the necessary stepping stones to achieve the ambitious goal of optimizing an individual's health via nutritional intervention.
Keywords
Animals, Coronary Disease, DNA, Complementary, Diabetes Mellitus, Food Technology, Genetic Predisposition to Disease, Genetic Variation, Genome, Health Food, Humans, Metabolism, Models, Biological, Nutritional Physiological Phenomena, Polymorphism, Genetic, Systems Biology
Pubmed
Web of science
Create date
24/01/2008 16:04
Last modification date
20/08/2019 16:03
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