Metastatic breast carcinoma in axillary lymph nodes: in vitro US detection

Details

Serval ID
serval:BIB_DDD1BFCA0826
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Metastatic breast carcinoma in axillary lymph nodes: in vitro US detection
Journal
Radiology
Author(s)
Feu  J., Tresserra  F., Fabregas  R., Navarro  B., Grases  P. J., Suris  J. C., Fernandez-Cid  A., Alegret  X.
ISSN
0033-8419 (Print)
Publication state
Published
Issued date
12/1997
Volume
205
Number
3
Pages
831-5
Notes
Comparative Study
In Vitro
Journal Article --- Old month value: Dec
Abstract
PURPOSE: To establish the ultrasonographic (US) characteristics of benign versus metastatic lymph nodes. MATERIALS AND METHODS: One hundred fifty-eight axillary lymph nodes in 40 patients (age range, 31-73 years) surgically treated for breast cancer have been studied in vitro with a 7.5-MHz US probe in a water bath. The long-to-short axis ratio and the hilar and cortical characteristics were evaluated; the US findings were correlated with the histopathologic findings. To estimate the long-to-short axis ratio, all lymph nodes were measured. RESULTS: Of the 158 lymph nodes, 45 showed histopathologic evidence of metastasis; 38 of the 45 revealed US signs of malignancy. The signs that caused malignancy to be suspected were a long-to-short axis ratio of less than 1.5, absence of a hilus, and disruption of the cortical zone. The most specific sign for the diagnosis of metastasis was absence of the hilus. The increase in the long-to-short axis ratio was the finding that caused the most false-negative interpretations. Signs of malignancy were more accurate in lymph nodes 10 mm or larger than they were in lymph nodes smaller than 10 mm. CONCLUSION: Findings of in vitro US studies of axillary adenopathy provide the basis for the evaluation of lymph node metastasis in vivo before surgery, especially in those lymph nodes 10 mm or larger.
Keywords
Axilla Breast Neoplasms/*pathology Carcinoma, Ductal, Breast/secondary/*ultrasonography Female Humans Logistic Models Lymph Nodes/pathology/*ultrasonography Lymphatic Metastasis Middle Aged Predictive Value of Tests Prospective Studies Sensitivity and Specificity
Pubmed
Web of science
Create date
25/01/2008 13:24
Last modification date
20/08/2019 16:02
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