Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020.
Details
Serval ID
serval:BIB_DCBAB64345ED
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020.
Journal
Lancet
Working group(s)
GBD 2020 Alcohol Collaborators
Contributor(s)
Reitsma M.B., Griswold M.G., Abate K.H., Abbafati C., Abbasi-Kangevari M., Abbasi-Kangevari Z., Abdoli A., Abdollahi M., Abdullah AYM, Abhilash E.S., Abu-Gharbieh E., Acuna J.M., Addolorato G., Adebayo O.M., Adekanmbi V., Adhikari K., Adhikari S., Adnani QES, Afzal S., Agegnehu W.Y., Aggarwal M., Ahinkorah B.O., Ahmad A.R., Ahmad S., Ahmad T., Ahmadi A., Ahmadi S., Ahmed H., Ahmed Rashid T., Akunna C.J., Al Hamad H., Alam M.Z., Alem D.T., Alene K.A., Alimohamadi Y., Alizadeh A., Allel K., Alonso J., Alvand S., Alvis-Guzman N., Amare F., Ameyaw E.K., Amiri S., Ancuceanu R., Anderson J.A., Andrei C.L., Andrei T., Arabloo J., Arshad M., Artamonov A.A., Aryan Z., Asaad M., Asemahagn M.A., Astell-Burt T., Athari S.S., Atnafu D.D., Atorkey P., Atreya A., Ausloos F., Ausloos M., Ayano G., Ayanore MAA, Ayinde O.O., Ayuso-Mateos J.L., Azadnajafabad S., Azanaw M.M., Azangou-Khyavy M., Azari Jafari A., Azzam A.Y., Badiye A.D., Bagheri N., Bagherieh S., Bairwa M., Bakkannavar S.M., Bakshi R.K., Balchut A.H., Bärnighausen T.W., Barra F., Barrow A., Baskaran P., Belo L., Bennett D.A., Benseñor I.M., Bhagavathula A.S., Bhala N., Bhalla A., Bhardwaj N., Bhardwaj P., Bhaskar S., Bhattacharyya K., Bhojaraja V.S., Bintoro B.S., Blokhina EAE, Bodicha BBA, Boloor A., Bosetti C., Braithwaite D., Brenner H., Briko N.I., Brunoni A.R., Butt Z.A., Cao C., Cao Y., Cárdenas R., Carvalho A.F., Carvalho M., Castaldelli-Maia J.M., Castelpietra G., Castro-de-Araujo LFS, Cattaruzza M.S., Chakraborty P.A., Charan J., Chattu V.K., Chaurasia A., Cherbuin N., Chu D.T., Chudal N., Chung S.C., Churko C., Ciobanu L.G., Cirillo M., Claro R.M., Costanzo S., Cowden R.G., Criqui M.H., Cruz-Martins N., Culbreth G.T., Dachew B.A., Dadras O., Dai X., Damiani G., Dandona L., Dandona R., Daniel B.D., Danielewicz A., Darega Gela J., Davletov K., de Araujo JAP, de Sá-Junior A.R., Debela S.A., Dehghan A., Demetriades A.K., Derbew Molla M., Desai R., Desta A.A., Dias da Silva D., Diaz D., Digesa L.E., Diress M., Dodangeh M., Dongarwar D., Dorostkar F., Dsouza H.L., Duko B., Duncan B.B., Edvardsson K., Ekholuenetale M., Elgar F.J., Elhadi M., Elmonem M.A., Endries A.Y., Eskandarieh S., Etemadimanesh A., Fagbamigbe A.F., Fakhradiyev I.R., Farahmand F., Farinha CSES, Faro A., Farzadfar F., Fatehizadeh A., Fauk N.K., Feigin V.L., Feldman R., Feng X., Fentaw Z., Ferrero S., Ferro Desideri L., Filip I., Fischer F., Francis J.M., Franklin R.C., Gaal P.A., Gad M.M., Gallus S., Galvano F., Ganesan B., Garg T., Gebrehiwot MGD, Gebremeskel T.G., Gebremichael M.A., Gemechu T.R., Getacher L., Getachew M.E., Getachew Obsa A., Getie A., Ghaderi A., Ghafourifard M., Ghajar A., Ghamari S.H., Ghandour L.A., Ghasemi Nour M., Ghashghaee A., Ghozy S., Glozah F.N., Glushkova E.V., Godos J., Goel A., Goharinezhad S., Golechha M., Goleij P., Golitaleb M., Greaves F., Grivna M., Grosso G., Gudayu T.W., Gupta B., Gupta R., Gupta S., Gupta V.B., Gupta V.K., Hafezi-Nejad N., Haj-Mirzaian A., Hall B.J., Halwani R., Handiso T.B., Hankey G.J., Hariri S., Haro J.M., Hasaballah A.I., Hassanian-Moghaddam H., Hay S.I., Hayat K., Heidari G., Heidari M., Hendrie D., Herteliu C., Heyi D.Z., Hezam K., Hlongwa M.M., Holla R., Hossain M.M., Hossain S., Hosseini S.K., Hosseinzadeh M., Hostiuc M., Hostiuc S., Hu G., Huang J., Hussain S., Ibitoye S.E., Ilic I.M., Ilic M.D., Immurana M., Irham L.M., Islam M.M., Islam R.M., Islam SMS, Iso H., Itumalla R., Iwagami M., Jabbarinejad R., Jacob L., Jakovljevic M., Jamalpoor Z., Jamshidi E., Jayapal S.K., Jayarajah U.U., Jayawardena R., Jebai R., Jeddi S.A., Jema A.T., Jha R.P., Jindal H.A., Jonas J.B., Joo T., Joseph N., Joukar F., Jozwiak J.J., Jürisson M., Kabir A., Kabthymer R.H., Kamble B.D., Kandel H., Kanno G.G., Kapoor N., Karaye I.M., Karimi S.E., Kassa B.G., Kaur R.J., Kayode G.A., Keykhaei M., Khajuria H., Khalilov R., Khan I.A., Khan M.A., Kim H., Kim J., Kim M.S., Kimokoti R.W., Kivimäki M., Klymchuk V., Knudsen AKS, Kolahi A.A., Korshunov V.A., Koyanagi A., Krishan K., Krishnamoorthy Y., Kumar G.A., Kumar N., Kumar N., Lacey B., Lallukka T., Lasrado S., Lau J., Lee S.W., Lee W.C., Lee Y.H., Lim L.L., Lim S.S., Lobo S.W., Lopukhov P.D., Lorkowski S., Lozano R., Lucchetti G., Madadizadeh F., Madureira-Carvalho Á.M., Mahjoub S., Mahmoodpoor A., Mahumud R.A., Makki A., Malekpour M.R., Manjunatha N., Mansouri B., Mansournia M.A., Martinez-Raga J., Martinez-Villa F.A., Matzopoulos R., Maulik P.K., Mayeli M., McGrath J.J., Meena J.K., Mehrabi Nasab E., Menezes R.G., Mensink GBM, Mentis A.A., Meretoja A., Merga B.T., Mestrovic T., Miao Jonasson J., Miazgowski B., Micheletti Gomide Nogueira de Sá A.C., Miller T.R., Mini G.K., Mirica A., Mirijello A., Mirmoeeni S., Mirrakhimov E.M., Misra S., Moazen B., Mobarakabadi M., Moccia M., Mohammad Y., Mohammadi E., Mohammadian-Hafshejani A., Mohammed T.A., Moka N., Mokdad A.H., Momtazmanesh S., Moradi Y., Mostafavi E., Mubarik S., Mullany E.C., Mulugeta B.T., Murillo-Zamora E., Murray CJL, Mwita J.C., Naghavi M., Naimzada M.D., Nangia V., Nayak B.P., Negoi I., Negoi R.I., Nejadghaderi S.A., Nepal S., Neupane SPP, Neupane Kandel S., Nigatu Y.T., Nowroozi A., Nuruzzaman K.M., Nzoputam C.I., Obamiro K.O., Ogbo F.A., Oguntade A.S., Okati-Aliabad H., Olakunde B.O., Oliveira GMM, Omar Bali A., Omer E., Ortega-Altamirano D.V., Otoiu A., Otstavnov S.S., Oumer B., P A M., Padron-Monedero A., Palladino R., Pana A., Panda-Jonas S., Pandey A., Pandey A., Pardhan S., Parekh T., Park E.K., Parry CDH, Pashazadeh Kan F., Patel J., Pati S., Patton G.C., Paudel U., Pawar S., Peden A.E., Petcu I.R., Phillips M.R., Pinheiro M., Plotnikov E., Pradhan PMS, Prashant A., Quan J., Radfar A., Rafiei A., Raghav P.R., Rahimi-Movaghar V., Rahman A., Rahman M.M., Rahman M., Rahmani A.M., Rahmani S., Ranabhat C.L., Ranasinghe P., Rao C.R., Rasali D.P., Rashidi M.M., Ratan Z.A., Rawaf D.L., Rawaf S., Rawal L., Renzaho AMN, Rezaei N., Rezaei S., Rezaeian M., Riahi S.M., Romero-Rodríguez E., Roth G.A., Rwegerera G.M., Saddik B., Sadeghi E., Sadeghian R., Saeed U., Saeedi F., Sagar R., Sahebkar A., Sahoo H., Sahraian M.A., Saif-Ur-Rahman K.M., Salahi S., Salimzadeh H., Samy A.M., Sanmarchi F., Santric-Milicevic M.M., Sarikhani Y., Sathian B., Saya G.K., Sayyah M., Schmidt M.I., Schutte A.E., Schwarzinger M., Schwebel D.C., Seidu A.A., Senthil Kumar N., SeyedAlinaghi S., Seylani A., Sha F., Shahin S., Shahraki-Sanavi F., Shahrokhi S., Shaikh M.A., Shaker E., Shakhmardanov M.Z., Shams-Beyranvand M., Sheikhbahaei S., Sheikhi R.A., Shetty A., Shetty J.K., Shiferaw D.S., Shigematsu M., Shiri R., Shirkoohi R., Shivakumar K.M., Shivarov V., Shobeiri P., Shrestha R., Sidemo N.B., Sigfusdottir I.D., Silva DAS, Silva NTD, Singh J.A., Singh S., Skryabin V.Y., Skryabina A.A., Sleet D.A., Solmi M., Solomon Y., Song S., Song Y., Sorensen RJD, Soshnikov S., Soyiri I.N., Stein D.J., Subba S.H., Szócska M., Tabarés-Seisdedos R., Tabuchi T., Taheri M., Tan K.K., Tareke M., Tarkang E.E., Temesgen G., Temesgen W.A., Temsah M.H., Thankappan K.R., Thapar R., Thomas N.K., Tiruneh C., Todorovic J., Torrado M., Touvier M., Tovani-Palone M.R., Tran MTN, Trias-Llimós S., Tripathy J.P., Vakilian A., Valizadeh R., Varmaghani M., Varthya S.B., Vasankari T.J., Vos T., Wagaye B., Waheed Y., Walde M.T., Wang C., Wang Y., Wang Y.P., Westerman R., Wickramasinghe N.D., Wubetu A.D., Xu S., Yamagishi K., Yang L., Yesera GEE, Yigit A., Yiğit V., Yimaw AEAE, Yon D.K., Yonemoto N., Yu C., Zadey S., Zahir M., Zare I., Zastrozhin M.S., Zastrozhina A., Zhang Z.J., Zhong C., Zmaili M., Zuniga YMH, Gakidou E.
ISSN
1474-547X (Electronic)
ISSN-L
0140-6736
Publication state
Published
Issued date
16/07/2022
Peer-reviewed
Oui
Volume
400
Number
10347
Pages
185-235
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
The health risks associated with moderate alcohol consumption continue to be debated. Small amounts of alcohol might lower the risk of some health outcomes but increase the risk of others, suggesting that the overall risk depends, in part, on background disease rates, which vary by region, age, sex, and year.
For this analysis, we constructed burden-weighted dose-response relative risk curves across 22 health outcomes to estimate the theoretical minimum risk exposure level (TMREL) and non-drinker equivalence (NDE), the consumption level at which the health risk is equivalent to that of a non-drinker, using disease rates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020 for 21 regions, including 204 countries and territories, by 5-year age group, sex, and year for individuals aged 15-95 years and older from 1990 to 2020. Based on the NDE, we quantified the population consuming harmful amounts of alcohol.
The burden-weighted relative risk curves for alcohol use varied by region and age. Among individuals aged 15-39 years in 2020, the TMREL varied between 0 (95% uncertainty interval 0-0) and 0·603 (0·400-1·00) standard drinks per day, and the NDE varied between 0·002 (0-0) and 1·75 (0·698-4·30) standard drinks per day. Among individuals aged 40 years and older, the burden-weighted relative risk curve was J-shaped for all regions, with a 2020 TMREL that ranged from 0·114 (0-0·403) to 1·87 (0·500-3·30) standard drinks per day and an NDE that ranged between 0·193 (0-0·900) and 6·94 (3·40-8·30) standard drinks per day. Among individuals consuming harmful amounts of alcohol in 2020, 59·1% (54·3-65·4) were aged 15-39 years and 76·9% (73·0-81·3) were male.
There is strong evidence to support recommendations on alcohol consumption varying by age and location. Stronger interventions, particularly those tailored towards younger individuals, are needed to reduce the substantial global health loss attributable to alcohol.
Bill & Melinda Gates Foundation.
For this analysis, we constructed burden-weighted dose-response relative risk curves across 22 health outcomes to estimate the theoretical minimum risk exposure level (TMREL) and non-drinker equivalence (NDE), the consumption level at which the health risk is equivalent to that of a non-drinker, using disease rates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020 for 21 regions, including 204 countries and territories, by 5-year age group, sex, and year for individuals aged 15-95 years and older from 1990 to 2020. Based on the NDE, we quantified the population consuming harmful amounts of alcohol.
The burden-weighted relative risk curves for alcohol use varied by region and age. Among individuals aged 15-39 years in 2020, the TMREL varied between 0 (95% uncertainty interval 0-0) and 0·603 (0·400-1·00) standard drinks per day, and the NDE varied between 0·002 (0-0) and 1·75 (0·698-4·30) standard drinks per day. Among individuals aged 40 years and older, the burden-weighted relative risk curve was J-shaped for all regions, with a 2020 TMREL that ranged from 0·114 (0-0·403) to 1·87 (0·500-3·30) standard drinks per day and an NDE that ranged between 0·193 (0-0·900) and 6·94 (3·40-8·30) standard drinks per day. Among individuals consuming harmful amounts of alcohol in 2020, 59·1% (54·3-65·4) were aged 15-39 years and 76·9% (73·0-81·3) were male.
There is strong evidence to support recommendations on alcohol consumption varying by age and location. Stronger interventions, particularly those tailored towards younger individuals, are needed to reduce the substantial global health loss attributable to alcohol.
Bill & Melinda Gates Foundation.
Keywords
Adult, Alcohol Drinking/adverse effects, Alcohol Drinking/epidemiology, Child, Preschool, Female, Geography, Global Burden of Disease, Global Health, Humans, Male, Middle Aged, Quality-Adjusted Life Years, Risk Factors
Pubmed
Web of science
Open Access
Yes
Create date
04/10/2022 12:19
Last modification date
07/03/2024 8:13
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