Point-shear wave elastography predicts liver hypertrophy after portal vein embolization and postoperative liver failure.
Details
Serval ID
serval:BIB_DCAC71847F8E
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Point-shear wave elastography predicts liver hypertrophy after portal vein embolization and postoperative liver failure.
Journal
Diagnostic and interventional imaging
ISSN
2211-5684 (Electronic)
ISSN-L
2211-5684
Publication state
Published
Issued date
06/2018
Peer-reviewed
Oui
Volume
99
Number
6
Pages
371-379
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
To correlate point-shear wave elastography (SWE) with liver hypertrophy after right portal vein embolization (RPVE) and to determine its usefulness in predicting postoperative liver failure in patients undergoing partial liver resection.
Point-SWE was performed the day before RPVE in 56 patients (41 men) with a median age of 66 years. The percentage (%) of future remnant liver (FRL) volume increase was defined as: %FRL <sub>post</sub> -%FRL <sub>pre</sub> %FRL <sub>pre</sub> ×100 and assessed on computed tomography performed 4 weeks after RPVE.
Median (range) %FRL <sub>pre</sub> and %FRL <sub>post</sub> was respectively, 31.5% (12-48%) and 41% (23-61%) (P<0.001), with a median %FRL volume increase of 25.6% (-8; 123%). SWE correlated with %FRL volume increase (P=-0.510; P<0.001). SWV (P=0.003) and %FRL <sub>pre</sub> (P<0.001) were associated with %FRL volume increase at multivariate regression analysis. Forty-three patients (77%) were operated. Postoperative liver failure occurred in 14 patients (32.5%). Median SWE was different between the group with (1.68m/s) and without liver failure (1.07m/s) (P=0.018). The AUROC of SWE predicting liver failure was 0.724 with a best cut-off of 1.31m/s, corresponding to a sensitivity of 21%, specificity of 96%, positive predictive value 75% and negative predictive value of 72%. SWE was the single independent preoperative variable associated with liver failure.
SWE assessed by point-SWE is a simple and useful tool to predict the FRL volume increase and postoperative liver failure in a population of patients with liver tumor.
Point-SWE was performed the day before RPVE in 56 patients (41 men) with a median age of 66 years. The percentage (%) of future remnant liver (FRL) volume increase was defined as: %FRL <sub>post</sub> -%FRL <sub>pre</sub> %FRL <sub>pre</sub> ×100 and assessed on computed tomography performed 4 weeks after RPVE.
Median (range) %FRL <sub>pre</sub> and %FRL <sub>post</sub> was respectively, 31.5% (12-48%) and 41% (23-61%) (P<0.001), with a median %FRL volume increase of 25.6% (-8; 123%). SWE correlated with %FRL volume increase (P=-0.510; P<0.001). SWV (P=0.003) and %FRL <sub>pre</sub> (P<0.001) were associated with %FRL volume increase at multivariate regression analysis. Forty-three patients (77%) were operated. Postoperative liver failure occurred in 14 patients (32.5%). Median SWE was different between the group with (1.68m/s) and without liver failure (1.07m/s) (P=0.018). The AUROC of SWE predicting liver failure was 0.724 with a best cut-off of 1.31m/s, corresponding to a sensitivity of 21%, specificity of 96%, positive predictive value 75% and negative predictive value of 72%. SWE was the single independent preoperative variable associated with liver failure.
SWE assessed by point-SWE is a simple and useful tool to predict the FRL volume increase and postoperative liver failure in a population of patients with liver tumor.
Keywords
Adult, Aged, Aged, 80 and over, Elasticity Imaging Techniques/methods, Embolization, Therapeutic/methods, Female, Humans, Hypertrophy, Liver/pathology, Liver Failure/diagnostic imaging, Liver Neoplasms/therapy, Male, Middle Aged, Portal Vein, Postoperative Complications/diagnostic imaging, Predictive Value of Tests, Retrospective Studies, Acoustic radiation force impulse (ARFI), Elastography, Point-share wave elastography (SWE), Portal vein embolization, Shear-wave velocity
Pubmed
Web of science
Create date
08/02/2018 18:05
Last modification date
20/08/2019 16:01