IgG4-related disease of the ureter: report of two cases and review of the literature.

Détails

ID Serval
serval:BIB_DBC7F1ABB3F6
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
IgG4-related disease of the ureter: report of two cases and review of the literature.
Périodique
Virchows Archiv : An International Journal of Pathology
Auteur(s)
Marando A., D'Ambrosio G., Catanzaro F., La Rosa S., Sessa F.
ISSN
1432-2307 (Electronic)
ISSN-L
0945-6317
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
462
Numéro
6
Pages
673-678
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article ; ReviewPublication Status: ppublish
Résumé
IgG4-related disease (IgG4-RD) is a recently recognized multi-organ fibro-inflammatory lesion characterized by elevated IgG4 serum levels and mass-forming lesions. This condition shows similar histological features independently of the site of origin including storiform fibrosis, obliterative phlebitis, and dense lymphoplasmacytic infiltrate with a conspicuous IgG4-positive plasma cell component. Since this disease has only recently been categorized as a single specific nosologic entity, lesions with these typical morphological features have previously been named in different ways, creating some confusion and making it difficult to identify cases published in the literature. Lesions with features suggesting IgG4-RDs have very rarely been reported in the ureter, and they have been named using the terms "inflammatory pseudotumor" and "idiopathic segmental ureteritis." Herein, we describe the clinicopathological features of ureteral IgG4-RD found in two different patients. An 82-year-old female and a 77-year-old male underwent ureteral resection due to severe ureteral wall thickness and lumen stenosis suggestive of urothelial carcinoma. However, histological examinations showed transmural fibro-inflammatory lesions, with abundant IgG4 plasma cells intermixed with histiocytes, lymphocytes, fibroblasts, and scattered eosinophils. We have also accurately reviewed the literature in order to identify, among lesions diagnosed with different names, examples of ureteral IgG4-related lesions to give the reader a comprehensive overview of this relatively rare inflammatory disease. We suggest using the name "ureteral IgG4-RD" for those lesions showing the same morphological features as IgG4-RDs located elsewhere.
Mots-clé
Aged, Aged, 80 and over, Eosinophils/pathology, Female, Fibroblasts/pathology, Histiocytes/pathology, Humans, Hypergammaglobulinemia/immunology, Hypergammaglobulinemia/pathology, Immunoglobulin G/blood, Lymphocytes/pathology, Male, Plasma Cells/immunology, Plasma Cells/pathology, Sclerosis/immunology, Sclerosis/pathology, Terminology as Topic, Treatment Outcome, Ureter/pathology, Ureter/surgery, Ureteral Diseases/immunology, Ureteral Diseases/pathology
Pubmed
Web of science
Création de la notice
06/09/2016 12:59
Dernière modification de la notice
20/08/2019 16:00
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