Molecular diagnosis and enrichment culture identified a septic pseudoarthrosis due to an infection with Erysipelatoclostridium ramosum.

Détails

Ressource 1Télécharger: 30772466 .pdf (763.53 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY-NC-ND 4.0
ID Serval
serval:BIB_DB839D64A53F
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Molecular diagnosis and enrichment culture identified a septic pseudoarthrosis due to an infection with Erysipelatoclostridium ramosum.
Périodique
International journal of infectious diseases
Auteur(s)
Zakham F., Pillonel T., Brunel A.S., Zambelli P.Y., Greub G., Croxatto A., Bertelli C.
ISSN
1878-3511 (Electronic)
ISSN-L
1201-9712
Statut éditorial
Publié
Date de publication
04/2019
Peer-reviewed
Oui
Volume
81
Pages
167-169
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Résumé
We describe here a rare case of septic pseudarthrosis due to Erysipelatoclostridium ramosum in a female young patient. The patient, currently in remission from Ewing's sarcoma treated by a bone resection and allograft combined with chemotherapy, suffered from a chronic femoral pseudarthrosis in a context of bone insufficiency and graft resorption. A broad range 16S PCR followed by sequencing, as well as an enrichment culture of a bone biopsy revealed the presence of E. ramosum, an anaerobic firmicute with a low Gram-positive affinity staining and low GC content, that was further characterized by whole genome sequencing (WGS).
Mots-clé
Adult, Clostridium/isolation & purification, Female, Femur, Humans, Pseudarthrosis/etiology, Bacterial genomics, Bone insufficiency, Clostridium ramosum, Erysipelatoclostridium ramosum, Graft resorption, Pseudoarthrosis, Taxogenomics
Pubmed
Web of science
Open Access
Oui
Création de la notice
06/03/2019 22:21
Dernière modification de la notice
20/08/2019 16:00
Données d'usage