Effect of transnasal insufflation on sleep disordered breathing in acute stroke: a preliminary study.

Détails

ID Serval
serval:BIB_DACAD708C81E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Effect of transnasal insufflation on sleep disordered breathing in acute stroke: a preliminary study.
Périodique
Sleep and Breathing
Auteur(s)
Haba-Rubio J., Andries D., Rey V., Michel P., Tafti M., Heinzer R.
ISSN
1522-1709 (Electronic)
ISSN-L
1520-9512
Statut éditorial
Publié
Date de publication
2012
Peer-reviewed
Oui
Volume
16
Numéro
3
Pages
759-764
Langue
anglais
Résumé
BACKGROUND AND PURPOSE: Sleep disordered breathing (SDB) is frequent in acute stroke patients and is associated with early neurologic worsening and poor outcome. Although continuous positive airway pressure (CPAP) effectively treats SDB, compliance is low. The objective of the present study was to assess the tolerance and the efficacy of a continuous high-flow-rate air administered through an open nasal cannula (transnasal insufflation, TNI), a less-intrusive method, to treat SDB in acute stroke patients.
METHODS: Ten patients (age, 56.8 ± 10.7 years), with SDB ranging from moderate to severe (apnea-hypopnea index, AHI, >15/h of sleep) and on a standard sleep study at a mean of 4.8 ± 3.7 days after ischemic stroke (range, 1-15 days), were selected. The night after, they underwent a second sleep study while receiving TNI (18 L/min).
RESULTS: TNI was well tolerated by all patients. For the entire group, TNI decreased the AHI from 40.4 ± 25.7 to 30.8 ± 25.7/h (p = 0.001) and the oxygen desaturation index >3% from 40.7 ± 28.4 to 31 ± 22.5/h (p = 0.02). All participants except one showed a decrease in AHI. The percentage of slow-wave sleep significantly increased with TNI from 16.7 ± 8.2% to 22.3 ± 7.4% (p = 0.01). There was also a trend toward a reduction in markers of sleep disruption (number of awakenings, arousal index).
CONCLUSIONS: TNI improves SDB indices, and possibly sleep parameters, in stroke patients. Although these changes are modest, our findings suggest that TNI is a viable treatment alternative to CPAP in patients with SDB in the acute phase of ischemic stroke.
Mots-clé
Transnasal insufflation, Stroke, Sleep disordered breathing
Pubmed
Web of science
Création de la notice
29/08/2011 8:31
Dernière modification de la notice
20/08/2019 16:59
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