Basic calcium phosphate crystals induce IL-1B secretion in vitro through activation of the Nalp3 inflammasome

Details

Serval ID
serval:BIB_D9C954BC4787
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Abstract (Abstract): shot summary in a article that contain essentials elements presented during a scientific conference, lecture or from a poster.
Collection
Publications
Institution
Title
Basic calcium phosphate crystals induce IL-1B secretion in vitro through activation of the Nalp3 inflammasome
Title of the conference
EULAR 2010, Annual European Congress of Rheumatology
Author(s)
Pazar B., Busso N., Kolly L., Narayan S., Bagnoud N., Chobaz V., Ea H.O., Lioté F., Yazdi A., Tschopp J., So A.
Address
Rome, Italy, June 16-19, 2010
ISBN
0003-4967
Publication state
Published
Issued date
2010
Peer-reviewed
Oui
Volume
69
Series
Annals of the Rheumatic Diseases
Pages
326
Language
english
Notes
Cytokines and inflammatory mediators
Abstract
Objectives: We tested the effects of the three forms of basic calcium phosphate (BCP) crystals (octacalcium phosphate (OCP), carbonate-substituted apatite (CA) and hydroxyapatite (HA)) on monocytes and macrophages on IL-1β secretion. The requirement for the NALP3 inflammasome and TLR2 and TLR4 receptors in this acute response was analyzed.
Create date
23/02/2011 12:00
Last modification date
20/08/2019 16:59
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