Vasopressin binding sites in the central nervous system: distribution and regulation

Details

Serval ID
serval:BIB_D98533913BD8
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Vasopressin binding sites in the central nervous system: distribution and regulation
Journal
Progress in Brain Research
Author(s)
Tribollet  E., Arsenijevic  Y., Barberis  C.
ISSN
0079-6123 (Print)
Publication state
Published
Issued date
1998
Volume
119
Pages
45-55
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review
Abstract
High affinity binding sites for vasopressin (VP) are widely distributed within the rat brain and spinal cord. Since their presence is associated with neuronal sensitivity to VP application, their anatomical distribution maps structures which could be activated by endogenous VP. Interestingly, marked species-related differences of the VP receptor distribution have been revealed. Some evidence has also been provided that mechanisms of receptor regulation may vary among species. In the rat, the expression of VP binding sites in some motor nuclei shows remarkable plasticity, in particular up-regulation after axotomy. These data suggest that VP may, in addition to affecting motoneuronal excitability, act as a trophic factor onto motoneurones.
Keywords
Animals Binding Sites/physiology Central Nervous System/*chemistry/cytology/*metabolism Motor Neurons/*chemistry/metabolism Rats Vasopressins/*analysis/*metabolism
Pubmed
Web of science
Create date
28/01/2008 12:31
Last modification date
20/08/2019 15:58
Usage data