Vasopressin binding sites in the central nervous system: distribution and regulation

Détails

ID Serval
serval:BIB_D98533913BD8
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Vasopressin binding sites in the central nervous system: distribution and regulation
Périodique
Progress in Brain Research
Auteur(s)
Tribollet  E., Arsenijevic  Y., Barberis  C.
ISSN
0079-6123 (Print)
Statut éditorial
Publié
Date de publication
1998
Volume
119
Pages
45-55
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review
Résumé
High affinity binding sites for vasopressin (VP) are widely distributed within the rat brain and spinal cord. Since their presence is associated with neuronal sensitivity to VP application, their anatomical distribution maps structures which could be activated by endogenous VP. Interestingly, marked species-related differences of the VP receptor distribution have been revealed. Some evidence has also been provided that mechanisms of receptor regulation may vary among species. In the rat, the expression of VP binding sites in some motor nuclei shows remarkable plasticity, in particular up-regulation after axotomy. These data suggest that VP may, in addition to affecting motoneuronal excitability, act as a trophic factor onto motoneurones.
Mots-clé
Animals Binding Sites/physiology Central Nervous System/*chemistry/cytology/*metabolism Motor Neurons/*chemistry/metabolism Rats Vasopressins/*analysis/*metabolism
Pubmed
Web of science
Création de la notice
28/01/2008 13:31
Dernière modification de la notice
03/03/2018 21:53
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