Photoreactivation of ultraviolet radiation-induced release of arachidonic acid from marsupial cells

Détails

ID Serval
serval:BIB_D93978BD372E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Photoreactivation of ultraviolet radiation-induced release of arachidonic acid from marsupial cells
Périodique
Photochemistry and Photobiology
Auteur(s)
Kaleta  E. W., Applegate  L. A., Ley  R. D.
ISSN
0031-8655 (Print)
Statut éditorial
Publié
Date de publication
1991
Volume
54
Numéro
5
Pages
747-752
Notes
DA - 19920413
LA - eng
PT - Journal Article
RN - 0 (Membrane Lipids)
RN - 0 (Phospholipids)
RN - 0 (Pyrimidine Dimers)
RN - 506-32-1 (Arachidonic Acid)
RN - EC 3.1.- (Endonucleases)
SB - IM
Résumé
Exposure of an established marsupial cell line, PtK2 (Potorous tridactylus), to ultraviolet radiation (UVR) from an FS-40 sunlamp (280-400 nm) resulted in a fluence-dependent release of radiolabeled arachidonic acid (AA) from cell membranes. Post-UVR, but not pre-UVR, exposure to photoreactivating light reversed UVR-induced pyrimidine dimers in DNA and suppressed the UVR-induced release of AA. These data indicate that DNA damage contributes to the release of AA from membrane phospholipids
Mots-clé
adverse effects/Animals/Arachidonic Acid/Cell Line/Cell Membrane/cytology/Dna/DNA Damage/DNA Repair/Dose-Response Relationship,Radiation/Endonucleases/Kidney/Light/Macropodidae/Membrane Lipids/Membranes/metabolism/Phospholipids/physiology/Pyrimidine Dimers/radiation effects/Ultraviolet Rays
Pubmed
Web of science
Création de la notice
18/02/2008 18:33
Dernière modification de la notice
20/08/2019 16:58
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