EEG-based functional networks in schizophrenia.

Details

Serval ID
serval:BIB_D9071F28186D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
EEG-based functional networks in schizophrenia.
Journal
Computers in Biology and Medicine
Author(s)
Jalili M., Knyazeva M.G.
ISSN
1879-0534 (Electronic)
ISSN-L
0010-4825
Publication state
Published
Issued date
2011
Volume
41
Number
12
Pages
1178-1186
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
Schizophrenia is often considered as a dysconnection syndrome in which, abnormal interactions between large-scale functional brain networks result in cognitive and perceptual deficits. In this article we apply the graph theoretic measures to brain functional networks based on the resting EEGs of fourteen schizophrenic patients in comparison with those of fourteen matched control subjects. The networks were extracted from common-average-referenced EEG time-series through partial and unpartial cross-correlation methods. Unpartial correlation detects functional connectivity based on direct and/or indirect links, while partial correlation allows one to ignore indirect links. We quantified the network properties with the graph metrics, including mall-worldness, vulnerability, modularity, assortativity, and synchronizability. The schizophrenic patients showed method-specific and frequency-specific changes especially pronounced for modularity, assortativity, and synchronizability measures. However, the differences between schizophrenia patients and normal controls in terms of graph theory metrics were stronger for the unpartial correlation method.
Pubmed
Web of science
Create date
24/02/2012 11:45
Last modification date
20/08/2019 16:58
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