Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Medicinal application of long synthetic peptide technology.
Expert opinion on biological therapy
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review - Publication Status: ppublish
This review covers the latest developments of long synthetic peptide technology for the rapid identification and development of malaria vaccine candidates and immunological modulators. A brief description of the two most common solid-phase synthetic procedures, together with the latest advances in optimisation of peptide chain assembly and analytical instrumentation, is given, with special attention to non-specialists. Several examples of vaccine candidates developed in the authors' or their collaborators' laboratories are also provided.
Animals, Antigens, Protozoan, B-Lymphocytes, Bee Venoms, Chemistry, Organic, Clinical Trials as Topic, Epitopes, Humans, Hypersensitivity, Immediate, Malaria Vaccines, Mice, Mice, Inbred BALB C, Peptides, Phospholipases A, Plasmodium falciparum, Plasmodium vivax, Protozoan Proteins, T-Lymphocyte Subsets, Vaccines, Subunit, Vaccines, Synthetic
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