Medicinal application of long synthetic peptide technology.
Details
Serval ID
serval:BIB_D8A7EF59A754
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Medicinal application of long synthetic peptide technology.
Journal
Expert opinion on biological therapy
ISSN
1744-7682[electronic]
Publication state
Published
Issued date
2004
Volume
4
Number
10
Pages
1629-39
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review - Publication Status: ppublish
Abstract
This review covers the latest developments of long synthetic peptide technology for the rapid identification and development of malaria vaccine candidates and immunological modulators. A brief description of the two most common solid-phase synthetic procedures, together with the latest advances in optimisation of peptide chain assembly and analytical instrumentation, is given, with special attention to non-specialists. Several examples of vaccine candidates developed in the authors' or their collaborators' laboratories are also provided.
Keywords
Animals, Antigens, Protozoan, B-Lymphocytes, Bee Venoms, Chemistry, Organic, Clinical Trials as Topic, Epitopes, Humans, Hypersensitivity, Immediate, Malaria Vaccines, Mice, Mice, Inbred BALB C, Peptides, Phospholipases A, Plasmodium falciparum, Plasmodium vivax, Protozoan Proteins, T-Lymphocyte Subsets, Vaccines, Subunit, Vaccines, Synthetic
Pubmed
Web of science
Create date
24/01/2008 14:55
Last modification date
20/08/2019 15:58
Usage data
