Dengue is a subject of major concern in global health because its incidence is increasing, and its geographical area continues to expand. On a global scale, the projections available point in the direction of an extension of the geographical areas of the Aedes vectors, partly in connection with the increase in temperatures and the modification of precipitation cycles in the context of the climate change. This expansion is expected at the borders of the areas of current spread with, however, a possible contraction in certain areas that are now endemic. In Europe, the threat of a dengue epidemic outbreak now exists. It is on this continent that the number of new exposures in immunologically naïve people is likely to be the greatest in the near future.