Inflammasomes in Host Defense and Autoimmunity.

Détails

ID Serval
serval:BIB_D7DFB5CC8C78
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Inflammasomes in Host Defense and Autoimmunity.
Périodique
Chimia
Auteur(s)
Broz P.
ISSN
0009-4293 (Print)
ISSN-L
0009-4293
Statut éditorial
Publié
Date de publication
21/12/2016
Peer-reviewed
Oui
Volume
70
Numéro
12
Pages
853-855
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
Inflammasomes are large multi-protein complexes that control host defense and inflammation during infections with pathogens. Their clinical importance however reaches beyond infectious disease, since dysregulated inflammasome activity has also been linked to many auto-inflammatory disorders. This article gives a short overview on the basics of inflammasome signaling, their activation mechanisms and their role in autoimmunity.

Mots-clé
Autoimmunity/immunology, Humans, Inflammasomes/immunology, Inflammasomes/metabolism, Inflammation/immunology, Inflammation/metabolism
Pubmed
Web of science
Création de la notice
25/10/2017 11:05
Dernière modification de la notice
20/08/2019 16:57
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