Male infertility: the intracellular bacterial hypothesis.

Détails

ID Serval
serval:BIB_D79FA9BEB917
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Male infertility: the intracellular bacterial hypothesis.
Périodique
New microbes and new infections
Auteur(s)
Stojanov M., Baud D., Greub G., Vulliemoz N.
ISSN
2052-2975 (Print)
ISSN-L
2052-2975
Statut éditorial
Publié
Date de publication
11/2018
Peer-reviewed
Oui
Volume
26
Pages
37-41
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Résumé
Infertility is a disease that affects one in seven couples. As male infertility affects approximately 30% of these couples with an unknown cause in half the cases, it represents a major public health concern. The classic treatment of male infertility involves intrauterine insemination, with modest outcome, and in vitro fertilization with intracytoplasmic sperm injection, which is known to be invasive and expensive, without treating the specific cause of infertility. Male fertility is mainly evaluated through a semen assessment where abnormal parameters such as concentration and motility can be associated with a decreased chance of conception. Infectious processes represent plausible candidates for male infertility. Chlamydia trachomatis is well known to cause female infertility through tubal damage but its role in male infertility remains controversial. The link between ureaplasmas/mycoplasmas and male infertility is also debatable. The potential negative impact of these bacteria on male fertility might not only involve semen parameters but also, as with C. trachomatis, include important physiological mechanisms such as fertilization processes that are not routinely assessed during infertility investigation. Basic research is important to help determine the exact effect of these bacteria on male fertility to develop targeted treatment and go beyond in vitro fertilization with intracytoplasmic sperm injection.
Mots-clé
Chlamydia, Mycoplasma, Ureaplasma, male infertility
Pubmed
Open Access
Oui
Création de la notice
02/10/2019 19:34
Dernière modification de la notice
08/10/2019 5:26
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