Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Knochenanabole Therapie mit Teriparatid [Bone anabolic treatment with Teriparatide].
Therapeutische Umschau. Revue Thérapeutique
Publication types: English Abstract ; Journal Article ; ReviewPublication Status: ppublish
The recombinant amino-terminal fragment of human parathyroid hormone (Teriparatide) is a bone anabolic agent which reduces fracture risk by increasing bone mass and improving bone microarchitecture. Teriparatide reduces vertebral fracture risk by 65 % and non-vertebral by 50 %. Its efficacy is higher as bisphosphonates to prevent corcicosteroid-induced osteoporosis. Teriparatide may also have a direct effect on bone pain. Teriparatide may be initiating immediately after an anticatabolic agent. However, it is not recommended to associate both treatments. At the end of teripatide treatment, an anticatabolic agent may be given. According to cost-effectiveness studies, Teriparatide should be considered as first line treatment for postmenopausal women and for men with severe osteoporosis.
Anabolic Agents/administration & dosage, Anabolic Agents/adverse effects, Bone Density Conservation Agents, Female, Fractures, Spontaneous/etiology, Fractures, Spontaneous/prevention & control, Humans, Male, Osteoporosis, Postmenopausal/complications, Osteoporosis, Postmenopausal/drug therapy, Teriparatide/administration & dosage, Teriparatide/adverse effects
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