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Case report (case report): feedback on an observation with a short commentary.
Wegener's granulomatosis: description of a case where cutaneous involvement was correlated with elevation of the c-ANCA titer
Wegener's granulomatosis is a systemic disease characterized by necrotizing granulomas and vasculitis involving the upper and lower respiratory tract as well as the kidneys. Cutaneous manifestations consist mainly of papules or papulonecrotic lesions. c-ANCA are known to be a valuable adjunct for the diagnosis and follow-up of Wegener's granulomatosis with systemic involvement. We report the case of a 49-year-old man with Wegener's granulomatosis who developed two relapses of the disease with cutaneous manifestation and who presented with concomitant elevation of the c-ANCA and more precisely the subset PR3-ANCA during the acute phase of the disease.
Antibodies, Antineutrophil Cytoplasmic/*blood Buttocks Elbow Humans Immunotherapy Leg Male Middle Aged *Neoplasm Recurrence, Local Skin Diseases/*pathology/therapy Wegener Granulomatosis/*pathology/therapy
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