Demographic History of the Human Commensal Drosophila melanogaster.

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Etat: Public
Version: Final published version
Licence: CC BY-NC 4.0
ID Serval
serval:BIB_D3DC4C3A672A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Demographic History of the Human Commensal Drosophila melanogaster.
Périodique
Genome biology and evolution
Auteur(s)
Arguello J.R., Laurent S., Clark A.G.
ISSN
1759-6653 (Electronic)
ISSN-L
1759-6653
Statut éditorial
Publié
Date de publication
01/03/2019
Peer-reviewed
Oui
Volume
11
Numéro
3
Pages
844-854
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
The cohabitation of Drosophila melanogaster with humans is nearly ubiquitous. Though it has been well established that this fly species originated in sub-Saharan Africa, and only recently has spread globally, many details of its swift expansion remain unclear. Elucidating the demographic history of D. melanogaster provides a unique opportunity to investigate how human movement might have impacted patterns of genetic diversity in a commensal species, as well as providing neutral null models for studies aimed at identifying genomic signatures of local adaptation. Here, we use whole-genome data from five populations (Africa, North America, Europe, Central Asia, and the South Pacific) to carry out demographic inferences, with particular attention to the inclusion of migration and admixture. We demonstrate the importance of these parameters for model fitting and show that how previous estimates of divergence times are likely to be significantly underestimated as a result of not including them. Finally, we discuss how human movement along early shipping routes might have shaped the present-day population structure of D. melanogaster.
Mots-clé
Animal Migration, Animals, Drosophila melanogaster/genetics, Gene Flow, Humans, Models, Genetic, Phylogeography, Polymorphism, Single Nucleotide, Transportation, Drosophila, admixture, demography, migration, population expansion
Pubmed
Open Access
Oui
Création de la notice
25/03/2019 9:22
Dernière modification de la notice
21/08/2019 7:10
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