Article: article from journal or magazin.
Staging of peritoneal carcinomatosis: enhanced CT vs. PET/CT
1432-0509 (Electronic)0942-8925 (Linking)
Dromain, ClarisseLeboulleux, SophieAuperin, AnneGoere, DianeMalka, DavidLumbroso, JeanSchumberger, MartinSigal, RobertElias, Dominiqueeng2007/07/17 09:00Abdom Imaging. 2008 Jan-Feb;33(1):87-93.
PURPOSE: To assess and compare the performance of CT and 18F-FDG-PET/CT in the evaluation of peritoneal carcinomatosis (PC). METHOD AND MATERIALS: Thirty consecutive patients with PC and scheduled for a surgery underwent a CT of the abdomen and pelvis and a whole-body 18F-FDG PET/CT. The extent of PC was assessed precisely using the peritoneal cancer index combining the distribution of tumor throughout 11 abdominopelvic regions with a lesion size score. CT and PET/CT imaging results were compared in all patients with intraoperative findings using an interclass correlation test. RESULTS: The presence of PC was correctly determined on CT and PET/CT in 23/28 and 16/28 patients, respectively. The extent of PC was understaged with CT and PET/CT in 27 patients and overstaged with CT and PET/CT in 1 and 2 patients, respectively. The interclass correlation was 0.53 (moderate) between CT and surgery and 0.12 (low) between PET/CT and surgery. The interclass correlation was higher for mucinous tumor (0.63) than for non-mucinous (0.16) on CT imaging whereas no difference was found in PET/CT. CONCLUSION: The intraperitoneal assessment of the extent of carcinomatosis, necessary to assess prognosis and treatment planning, is not accurate enough with CT and PET/CT imaging.
Adult, Contrast Media, Female, Fluorodeoxyglucose F18, Gastrointestinal Neoplasms/pathology, Humans, Iohexol, Male, Middle Aged, Neoplasm Staging, Peritoneal Neoplasms/*radiography/*radionuclide imaging/secondary, Prospective Studies, Radiopharmaceuticals, Sensitivity and Specificity, *Tomography, Emission-Computed, *Tomography, X-Ray Computed
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