Bioelectrical impedance in young patients with cystic fibrosis: Validation of a specific equation and clinical relevance.
Details
Serval ID
serval:BIB_D1F89CDBDA53
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Bioelectrical impedance in young patients with cystic fibrosis: Validation of a specific equation and clinical relevance.
Journal
Journal of cystic fibrosis
ISSN
1873-5010 (Electronic)
ISSN-L
1569-1993
Publication state
Published
Issued date
11/2016
Peer-reviewed
Oui
Volume
15
Number
6
Pages
825-833
Language
english
Notes
Publication types: Journal Article ; Validation Study
Publication Status: ppublish
Publication Status: ppublish
Abstract
Body composition (BC) analysis based on bioelectrical impedance analysis (BIA) provides conflicting results. The purpose of the study was to validate an equation specific for young patients with cystic fibrosis (CF), describe their BC and investigate its association with lung function.
Fifty-four young CF patients were evaluated by BIA and dual X-ray absorptiometry (DXA). An empirically derived CF-specific equation for fat-free mass (FFM) estimation by BIA was elaborated after stepwise multivariate regression and the agreement between BIA and DXA was assessed by Bland-Altman plots. The association between BC and lung function was investigated by regression analysis.
The mean difference between the BIA and DXA assessment was close to zero. A total of 22.5% of patients (n=9) presented a FFM z-score≤-2. They had a worse pulmonary function and diaphragmatic impairment. Among these 9 patients, 7 had a normal BMI z-score>-1.
BIA, based on a CF-specific equation, is a reliable method for BC assessment and allows the identification of patients at risk of nutritional degradation and bad respiratory prognosis.
Fifty-four young CF patients were evaluated by BIA and dual X-ray absorptiometry (DXA). An empirically derived CF-specific equation for fat-free mass (FFM) estimation by BIA was elaborated after stepwise multivariate regression and the agreement between BIA and DXA was assessed by Bland-Altman plots. The association between BC and lung function was investigated by regression analysis.
The mean difference between the BIA and DXA assessment was close to zero. A total of 22.5% of patients (n=9) presented a FFM z-score≤-2. They had a worse pulmonary function and diaphragmatic impairment. Among these 9 patients, 7 had a normal BMI z-score>-1.
BIA, based on a CF-specific equation, is a reliable method for BC assessment and allows the identification of patients at risk of nutritional degradation and bad respiratory prognosis.
Keywords
Absorptiometry, Photon/methods, Adolescent, Body Composition, Body Mass Index, Child, Cystic Fibrosis/diagnosis, Cystic Fibrosis/physiopathology, Electric Impedance, Female, France, Humans, Male, Prognosis, Prospective Studies, Respiratory Function Tests/methods, Statistics as Topic, Young Adult, Bioelectrical impedance analysis, Body composition, Cystic fibrosis, Diaphragm, Fat-free mass, Lung function
Pubmed
Web of science
Open Access
Yes
Create date
03/07/2023 16:05
Last modification date
04/07/2023 5:55
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