An optimized antigen-protein fusion.

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Serval ID
serval:BIB_D08755FBF911
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Institution
UNIL/CHUV
Title
An optimized antigen-protein fusion.
Journal
Nature biomedical engineering
Author(s)
Romero P., Donda A., Hubbell J.A.
ISSN
2157-846X (Electronic)
ISSN-L
2157-846X
Publication state
Published
Issued date
06/2020
Peer-reviewed
Oui
Volume
4
Number
6
Pages
583-584
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
The fusion of an immunogenic peptide and the protein transthyretin protects the peptide antigen from proteolytic degradation, optimizes its uptake in local draining lymphatics and reduces its presentation in uninflamed distal lymphoid organs, as shown in mice.
OAI-PMH
oai:serval.unil.ch:BIB_D08755FBF911
DOI
10.1038/s41551-020-0572-3
Pubmed
32533123
Web of science
000540171700005
Create date
25/06/2020 14:56
Last modification date
12/01/2021 6:25
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