Social regulation of insulin signaling and the evolution of eusociality in ants.

Détails

ID Serval
serval:BIB_CDF17CA820DE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Social regulation of insulin signaling and the evolution of eusociality in ants.
Périodique
Science
Auteur(s)
Chandra V., Fetter-Pruneda I., Oxley P.R., Ritger A.L., McKenzie S.K., Libbrecht R., Kronauer DJC
ISSN
1095-9203 (Electronic)
ISSN-L
0036-8075
Statut éditorial
Publié
Date de publication
27/07/2018
Peer-reviewed
Oui
Volume
361
Numéro
6400
Pages
398-402
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural
Publication Status: ppublish
Résumé
Queens and workers of eusocial Hymenoptera are considered homologous to the reproductive and brood care phases of an ancestral subsocial life cycle. However, the molecular mechanisms underlying the evolution of reproductive division of labor remain obscure. Using a brain transcriptomics screen, we identified a single gene, <i>insulin-like peptide 2</i> ( <i>ilp2</i> ), which is always up-regulated in ant reproductives, likely because they are better nourished than their nonreproductive nestmates. In clonal raider ants ( <i>Ooceraea biroi</i> ), larval signals inhibit adult reproduction by suppressing <i>ilp2</i> , thus producing a colony reproductive cycle reminiscent of ancestral subsociality. However, increasing ILP2 peptide levels overrides larval suppression, thereby breaking the colony cycle and inducing a stable division of labor. These findings suggest a simple model for the origin of ant eusociality via nutritionally determined reproductive asymmetries potentially amplified by larval signals.
Mots-clé
Animals, Ants/genetics, Ants/growth & development, Ants/metabolism, Biological Evolution, Brain/metabolism, Gene Expression, Insulin/genetics, Insulin/metabolism, Larva/genetics, Larva/growth & development, Larva/metabolism, Reproduction, Signal Transduction, Social Behavior
Pubmed
Web of science
Création de la notice
15/08/2018 8:50
Dernière modification de la notice
30/10/2018 7:26
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