Nonpharmacological therapy for refractory arrhythmias

Details

Serval ID
serval:BIB_CD57824AD0BA
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Nonpharmacological therapy for refractory arrhythmias
Journal
Journal of Cardiovascular Pharmacology
Author(s)
Kappenberger  L.
ISSN
0160-2446 (Print)
Publication state
Published
Issued date
1991
Volume
17 Suppl 6
Pages
S87-90
Notes
Journal Article
Review
Abstract
Because the great majority of clinically relevant arrhythmias are based on the principle of reentry, the understanding of the basic principle of this mechanism leads to alternative nonpharmacological therapy for such arrhythmias. The reentry circuit might be interrupted definitively by surgical or catheter ablative procedures, such as DC-energy shock delivery or radiofrequency coagulation, which will both lead to complete prevention of the tachycardia. On the other hand, electrical stimulation may influence the circus movement by wavefront collision and thus interrupt the tachycardia after it started. Antitachycardia pacemakers work on this principle. One major impact of antiarrhythmic treatment is the prevention of sudden death. The implantable defibrillator is currently the only treatment that really proves to be reliable in aborting sudden death. It is therefore the "gold standard" of antiarrhythmic treatment in life-threatening arrhythmias.
Keywords
Anti-Arrhythmia Agents/*therapeutic use Arrhythmia/drug therapy/*therapy Drug Resistance Electric Countershock Humans Tachycardia/therapy
Pubmed
Web of science
Create date
15/02/2008 11:29
Last modification date
20/08/2019 15:48
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