Markers for sepsis diagnosis in the forensic setting: state of the art.

Détails

Ressource 1Télécharger: BIB_CCFE5F29591E.P001.pdf (226.21 [Ko])
Etat: Serval
Version: Final published version
ID Serval
serval:BIB_CCFE5F29591E
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Markers for sepsis diagnosis in the forensic setting: state of the art.
Périodique
Croatian Medical Journal
Auteur(s)
Palmiere C., Augsburger M.
ISSN
1332-8166 (Electronic)
ISSN-L
0353-9504
Statut éditorial
Publié
Date de publication
2014
Volume
55
Numéro
2
Pages
103-114
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
Reliable diagnoses of sepsis remain challenging in forensic pathology routine despite improved methods of sample collection and extensive biochemical and immunohistochemical investigations. Macroscopic findings may be elusive and have an infectious or non-infectious origin. Blood culture results can be difficult to interpret due to postmortem contamination or bacterial translocation. Lastly, peripheral and cardiac blood may be unavailable during autopsy. Procalcitonin, C-reactive protein, and interleukin-6 can be measured in biological fluids collected during autopsy and may be used as in clinical practice for diagnostic purposes. However, concentrations of these parameters may be increased due to etiologies other than bacterial infections, indicating that a combination of biomarkers could more effectively discriminate non-infectious from infectious inflammations. In this article, we propose a review of the literature pertaining to the diagnostic performance of classical and novel biomarkers of inflammation and bacterial infection in the forensic setting.
Pubmed
Web of science
Création de la notice
30/04/2014 14:25
Dernière modification de la notice
03/03/2018 21:29
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