Plasticity in the barrel cortex of the adult mouse: transient increase of GAD-immunoreactivity following sensory stimulation

Détails

ID Serval
serval:BIB_CCE2563B6137
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Plasticity in the barrel cortex of the adult mouse: transient increase of GAD-immunoreactivity following sensory stimulation
Périodique
Experimental Brain Research
Auteur(s)
Welker  E., Soriano  E., Dorfl  J., Van der Loos  H.
ISSN
0014-4819 (Print)
Statut éditorial
Publié
Date de publication
1989
Volume
78
Numéro
3
Pages
659-64
Notes
Journal Article
Research Support, Non-U.S. Gov't
Résumé
Sensory experience during perinatal life and adulthood modifies physiological and anatomical characteristics of the central nervous system. So far, this phenomenon has been studied in situations of complete or partial sensory deprivation. We here report that increased sensory stimulation, during four days, of a number of whisker follicles on the face of the adult mouse results in an increased immunoreactivity of glutamic acid decarboxylase (the biosynthetic enzyme of the inhibitory neurotransmitter GABA) in the somatosensory cortex of the adult mouse. Effects were limited to a column of tissue corresponding to the representation of the stimulated follicles and lasted two days beyond stimulation. These findings suggest that sensory stimulation transiently modifies local cortical processing.
Mots-clé
Animals Glutamate Decarboxylase/*metabolism Immunohistochemistry Mechanoreceptors/enzymology/*physiology Mice *Neuronal Plasticity Physical Stimulation Somatosensory Cortex/enzymology/*physiology Vibrissae/*physiology
Pubmed
Web of science
Création de la notice
24/01/2008 15:40
Dernière modification de la notice
03/03/2018 21:29
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