Statines et effets indésirables musculaires [Statins and muscular side-effects]

Détails

ID Serval
serval:BIB_CCDC48850EED
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Statines et effets indésirables musculaires [Statins and muscular side-effects]
Périodique
Revue Médicale Suisse
Auteur(s)
Brosteaux C., Ruiz J., Buclin T., Kuntzer T., Rodondi N.
ISSN
1660-9379[print], 1660-9379[linking]
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
6
Numéro
239
Pages
510-517
Langue
français
Notes
Publication types: Comparative Study ; English Abstract ; Journal Article ; Review
Résumé
Statins are effective in the treatment of hypercholesterolemia for primary and secondary prevention of cardiovascular disease. While most side effects of statins are mild and transient, muscular symptoms are relatively common (5 to 10% of patients), but rarely serious (myositis, rhabdomyolysis). In cases of myopathy, the severity of symptoms and the determination of CK (creatine kinase) determine whether discontinuation of statin is necessary. Alternative strategies are also suggested. This article reviews suggestions on the management of these complaints that are a challenge in clinical practice.
Mots-clé
Age Factors, Aged, 80 and over, Algorithms, Anticholesteremic Agents/administration & dosage, Anticholesteremic Agents/adverse effects, Azetidines/administration & dosage, Azetidines/therapeutic use, Biopsy, Cardiovascular Diseases/prevention & control, Creatine Kinase/blood, Female, Humans, Life Style, Male, Muscle, Skeletal/pathology, Muscular Diseases/blood, Muscular Diseases/chemically induced, Myositis/chemically induced, Pain/chemically induced, Primary Prevention, Randomized Controlled Trials as Topic, Retrospective Studies, Rhabdomyolysis/chemically induced, Secondary Prevention, Sex Factors, Ubiquinone/deficiency
Pubmed
Création de la notice
04/11/2010 16:30
Dernière modification de la notice
03/03/2018 21:29
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