Central line sepsis in intensive care units : overview and update

Détails

ID Serval
serval:BIB_CC5F0F4149D3
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Central line sepsis in intensive care units : overview and update
Périodique
Current Anaesthesia and Critical Care
Auteur(s)
Eggimann P., Pittet D.
ISSN
0953-7112
Statut éditorial
Publié
Date de publication
1999
Volume
10
Numéro
1
Pages
14-20
Langue
anglais
Résumé
Catheter-related infection remains a leading cause of nosocomial infections, particularly in intensive care units. It includes colonization of the device, skin exit-site infection and device- or catheter-related bloodstream infection. The latter represents the most frequent life-threatening associated complication of central venous catheter use and is associated with significant patient morbidity, mortality and extra hospital costs. The incidence of catheter-related bloodstream infection ranges from 2 to 14 episodes per 1000 catheter-days. On average, microbiologically-documented device-related bloodstream infections complicate from three to five per 100 central venous line uses, but they only represent the visible part of the iceberg and most clinical sepsis are nowadays considered to be catheter-related. We briefly review the pathophysiology of infection, highlighting the importance of the skin insertion site and of intravenous line hub as principal sources of colonization. Principles of therapy are reviewed. Several preventive approaches are also discussed, in particular the possible benefit of recently developed impregnated catheters. Finally, the potential positive impact of a multimodal global preventive strategy based on strict application of hygienic rules is presented.
Création de la notice
06/10/2009 18:05
Dernière modification de la notice
03/03/2018 21:28
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