Hippocampal-neocortical interaction: a hierarchy of associativity

Détails

ID Serval
serval:BIB_CC53830647D0
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Hippocampal-neocortical interaction: a hierarchy of associativity
Périodique
Hippocampus
Auteur(s)
Lavenex P., Amaral D.G.
ISSN
1050-9631 (Print)
1098-1063 (Online)
ISSN-L
1050-9631
Statut éditorial
Publié
Date de publication
2000
Peer-reviewed
Oui
Volume
10
Numéro
4
Pages
420-430
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S. ; Review
Publication Status: ppublish
Résumé
The structures forming the medial temporal lobe appear to be necessary for the establishment of long-term declarative memory. In particular, they may be involved in the "consolidation" of information in higher-order associational cortices, perhaps through feedback projections. This review highlights the fact that the medial temporal lobe is organized as a hierarchy of associational networks. Indeed, associational connections within the perirhinal, parahippocampal, and entorhinal cortices enables a significant amount of integration of unimodal and polymodal inputs, so that only highly integrated information reaches the remainder of the hippocampal formation. The feedback efferent projections from the perirhinal and parahippocampal cortices to the neocortex largely reciprocate the afferent projections from the neocortex to these areas. There are, however, noticeable differences in the degree of reciprocity of connections between the perirhinal and parahippocampal cortices and certain areas of the neocortex, in particular in the frontal and temporal lobes. These observations are particularly important for models of hippocampal-neocortical interaction and long-term storage of information in the neocortex. Furthermore, recent functional studies suggest that the perirhinal and parahippocampal cortices are more than interfaces for communication between the neocortex and the hippocampal formation. These structures participate actively in memory processes, but the precise role they play in the service of memory or other cognitive functions is currently unclear.
Mots-clé
Animals, Association, Entorhinal Cortex/anatomy & histology, Entorhinal Cortex/physiology, Hippocampus/physiology, Humans, Memory/physiology, Neocortex/physiology, Parahippocampal Gyrus/anatomy & histology, Parahippocampal Gyrus/physiology
Pubmed
Création de la notice
13/10/2014 19:00
Dernière modification de la notice
20/08/2019 16:47
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