Esophageal cancer as second primary tumor after breast cancer radiotherapy

Détails

ID Serval
serval:BIB_CBC3EC80A46A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Esophageal cancer as second primary tumor after breast cancer radiotherapy
Périodique
American Journal of Surgery
Auteur(s)
Scholl  B., Reis  E. D., Zouhair  A., Chereshnev  I., Givel  J. C., Gillet  M.
ISSN
0002-9610 (Print)
Statut éditorial
Publié
Date de publication
11/2001
Volume
182
Numéro
5
Pages
476-80
Notes
Journal Article --- Old month value: Nov
Résumé
BACKGROUND: An increased risk of esophageal cancer has been reported in survivors of breast cancer treated with radiotherapy. This study further characterizes this association. METHODS: Through hospital databases, 118 patients (109 men, 9 women) treated for esophageal cancer between 1985 and 1993 were identified, of whom 37 had 60 synchronous or metachronous cancers. 5 women had primary esophageal cancer after having breast cancer, and are the subjects of this case-control study. RESULTS: All 5 women had been treated with radical mastectomy and adjuvant radiotherapy; none received chemotherapy. Their ages at the time of breast cancer ranged from 36 to 82 years; at esophageal cancer, 61 to 95 years. Time between radiotherapy and esophageal cancer varied from 13 to 31 years. All esophageal cancers were squamous cell carcinomas. Mean survival after esophageal cancer was 14.2 months. CONCLUSIONS: Radio-induced esophageal cancer can occur as a second primary cancer in women who survive at least 1 decade after mastectomy and adjuvant radiotherapy.
Mots-clé
Adult Aged Aged, 80 and over Breast Neoplasms/*radiotherapy Breast Neoplasms, Male/radiotherapy Carcinoma, Squamous Cell/*etiology Esophageal Neoplasms/*etiology Female Humans Male Middle Aged *Neoplasms, Radiation-Induced Neoplasms, Second Primary/*etiology
Pubmed
Web of science
Création de la notice
28/01/2008 9:56
Dernière modification de la notice
03/03/2018 21:27
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