On nature and limits of cortical developmental plasticity after an early lesion, in a child.

Détails

ID Serval
serval:BIB_CB74B3438810
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
On nature and limits of cortical developmental plasticity after an early lesion, in a child.
Périodique
Restorative Neurology and Neuroscience
Auteur(s)
Innocenti G.M., Kiper D.C., Knyazeva M.G., Deonna T.W.
ISSN
0922-6028[print], 0922-6028[linking]
Statut éditorial
Publié
Date de publication
1999
Volume
15
Numéro
2-3
Pages
219-227
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
MS is a little girl who suffered severe, bilateral destruction of her primary visual areas at six weeks, after premature birth at 30 weeks. Between the ages of 4.5 and 5.5 years she partially recovered different aspects of visual function, and, in particular, the ability to segregate figures from background, based on texture cues. The recovery might have been due to the compensatory role of the remaining visual areas that could have acquired response properties similar to those of the primary visual areas. This is not supported by the available FMRI (functional magnetic resonance imaging) responses to visual stimuli. Instead, abnormalities in the pattern of stimulus-induced changes of interhemi-spheric EEG-coherence in this patient suggest that her visual callosal connections, and possibly other cortico-cortical connections have re-organized abnormally. Since cortico-cortical connections, including the callosal ones appear to be involved in perceptual binding and figure-background segregation, their reorganization could be an important element in the functional recovery after early lesion, and/or in the residual perceptual impairment.
Pubmed
Web of science
Création de la notice
11/04/2008 13:20
Dernière modification de la notice
03/03/2018 21:26
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